CAJ | 학술논문

“蛋白质组学”一词由Wilkins在1994年提出,被称作后基因组时代一个新兴的研究手段.它从整体水平上对组织或者细胞的蛋白质表达、功能、相互作用进行研究,现在成为生命科学未来发展的主要分支之一.睾丸是哺乳动物雄性生殖系统中的一个重要的器官,由曲精小管和间质细胞组成.蛋白质组学在睾丸和精子发生研究上的应用及其技术手段的不断创新,对睾丸功能、生殖机理、生殖疾病的研究起到了极其重要的作用.所以,从蛋白质水平对睾丸和精子发生进行研究,为更好地理解雄性哺乳动物的生殖机理和疾病提供了一个新思路.
“단백질조학”일사유Wilkins재1994년제출,피칭작후기인조시대일개신흥적연구수단.타종정체수평상대조직혹자세포적단백질표체、공능、상호작용진행연구,현재성위생명과학미래발전적주요분지지일.고환시포유동물웅성생식계통중적일개중요적기관,유곡정소관화간질세포조성.단백질조학재고환화정자발생연구상적응용급기기술수단적불단창신,대고환공능、생식궤리、생식질병적연구기도료겁기중요적작용.소이,종단백질수평대고환화정자발생진행연구,위경호지리해웅성포유동물적생식궤리화질병제공료일개신사로.
Proteomics, a name proposed initially by Wilkins in 1994, is considered as a new research area in that has developed in the post-genome era. It describes research into the expression, functions and interactions of pro-teins in organs or cells, and has developed rapidly to become an important branch in the life science. The testis, which comprise mainly seminiferous tubules and leydig cells, is a vital organ in the male mammal reproductive sys-tem. Proteomics has played an important role in reaching the function of testis, reproductive mechanism and male genital disease. The use of proteomics to study testis development and spermatogenesis represents a novel approach for better understanding the reproductive mechanism and disease of male mammals.