CAJ | 학술논문

目的探讨无创正压通气(NPPV)治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的临床治疗效果.方法选择东莞市人民医院收治的106例COPD合并Ⅱ型呼吸衰竭患者为研究对象,随机分为治疗组和对照组,每组各53例,两组患者均行吸氧、抗感染、对症等常规治疗,治疗组在常规治疗的同时加用无创正压通气治疗,比较两组患者治疗前后的动脉血气和临床指标变化.结果两组患者治疗后pH、PaO 2、PaCO 2等血气指标均优于治疗前,差异具有统计学意义(P<0.05),治疗组比对照组改善更为明显(P<0.05);与对照组比较,治疗组的住院天数、插管率及病死率均下降或缩短,差异具有统计学意义(P<0.05).结论 COPD合并Ⅱ型呼吸衰竭在常规治疗的同时加用NPPV可提高治疗效果,降低并发症的发生率和死亡率,值得临床推广应用.
목적탐토무창정압통기(NPPV)치료만성조새성폐질병(COPD)합병Ⅱ형호흡쇠갈적림상치료효과.방법선택동완시인민의원수치적106례COPD합병Ⅱ형호흡쇠갈환자위연구대상,수궤분위치료조화대조조,매조각53례,량조환자균행흡양、항감염、대증등상규치료,치료조재상규치료적동시가용무창정압통기치료,비교량조환자치료전후적동맥혈기화림상지표변화.결과량조환자치료후pH、PaO 2、PaCO 2등혈기지표균우우치료전,차이구유통계학의의(P<0.05),치료조비대조조개선경위명현(P<0.05);여대조조비교,치료조적주원천수、삽관솔급병사솔균하강혹축단,차이구유통계학의의(P<0.05).결론 COPD합병Ⅱ형호흡쇠갈재상규치료적동시가용NPPV가제고치료효과,강저병발증적발생솔화사망솔,치득림상추엄응용.
Objective To investigate the clinical curative effect of noninvasive positive pressure ventilation(NPPV)treatment of COPD combined TypeⅡrespiratory failure. Methods 106 patients were randomly divided into treatment group and control group the 53 cases, two groups of patients were performed with oxygen, resistance to infection, suit and conventional treatment, the treatment group in the conventional treatment at the same time to add NPPV treatment, compared between the two groups before and after treatment in patients with the arterial blood gas and clinical indicators.Results Two groups of patients after treatment, the pH, PaO 2, PaCO 2 and gas indexes is better than the before treatment, the difference is statistically significant (P<0.05), the treatment group than the control group is more obvious improvement (P<0.05); Comparing with control group, the treatment group in days, intubation rate and mortality decreased or shorten, a statistically significant difference (P<0.05).Conclusion COPD combined TypeⅡrespiratory failure in the conventional treatment at the same time to add a NPPV can improve the treatment effect, to reduce the incidence of complications and mortality, it is worth clinical promotion.