CAJ | 학술논문

目的探讨生理性海水喷雾洗鼻液对儿童轻度间歇性变应性鼻炎(AR)的临床疗效.方法选取2009~2012年的60例鼻炎患儿,随机分为对照组和试验组.对照组30例,采用氯雷他定治疗,试验组30例,采用生理性海水喷雾洗鼻液治疗.结果对照组和试验组治疗前鼻炎症状评分相比无显著差异(P>0.05),治疗后第4周对照组鼻炎症状评分(1.5±0.7),试验组鼻炎症状评分(0.9±0.3),试验组治疗后鼻炎症状评分小于对照组,差异显著(P<0.05).试验组和对照组治疗后鼻炎症状评分均小于治疗前,差异显著(P<0.05).对照组总有效率为73.33%,试验组96.67%,试验组总有效率大于对照组,差异显著(P<0.05).结论采用生理性海水喷雾洗鼻液治疗儿童轻度间歇性变应性鼻炎能显著改善患儿鼻炎症状,效果优于与抗组胺药物,在临床上具有推广意义.
목적탐토생이성해수분무세비액대인동경도간헐성변응성비염(AR)적림상료효.방법선취2009~2012년적60례비염환인,수궤분위대조조화시험조.대조조30례,채용록뢰타정치료,시험조30례,채용생이성해수분무세비액치료.결과대조조화시험조치료전비염증상평분상비무현저차이(P>0.05),치료후제4주대조조비염증상평분(1.5±0.7),시험조비염증상평분(0.9±0.3),시험조치료후비염증상평분소우대조조,차이현저(P<0.05).시험조화대조조치료후비염증상평분균소우치료전,차이현저(P<0.05).대조조총유효솔위73.33%,시험조96.67%,시험조총유효솔대우대조조,차이현저(P<0.05).결론채용생이성해수분무세비액치료인동경도간헐성변응성비염능현저개선환인비염증상,효과우우여항조알약물,재림상상구유추엄의의.
Objective To investigate the clinical effect of physiological seawater nasal irrigation in treatment of mild intermittent allergic rhinitis in children. Methods During 2009 to 2012, 60 pediatric cases were randomLy selected and divided into two groups. Control group included 30 cases used loratadine, and test group included 30 cases used physiological seawater nasal irrigation. Results AR symptom score after treatment of control group is(1.5±0.7) and test group is (0.9±0.3). The score of test group is less than control group. The difference ofAR symptom scores between the two groups was statistically significant (P<0.05). The total efficiency of the control group was 73.33%, while test group was 96.67% , the difference of the two groups was statistically significant. Conclusion Physiological seawater nasal irrigation can have a better clinical effect than antihistamine on mild intermittent allergic rhinitis of children, and can be popularized.