CAJ | 학술논문

丙型肝炎病毒(HCV)入侵宿主细胞是在多种受体联合介导下才能完成的复杂过程.我们针对已报道的HCV 可能的细胞受体 CD81、低密度脂蛋白受体、B 族Ⅰ型清道夫受体、紧密连接蛋白家族、表皮生长子受体、酪氨酸激酶 EphA2受体、NPC1L1受体展开介绍,为今后研究和探索新型 HCV 疫苗和药物奠定基础.
병형간염병독(HCV)입침숙주세포시재다충수체연합개도하재능완성적복잡과정.아문침대이보도적HCV 가능적세포수체 CD81、저밀도지단백수체、B 족Ⅰ형청도부수체、긴밀련접단백가족、표피생장자수체、락안산격매 EphA2수체、NPC1L1수체전개개소,위금후연구화탐색신형 HCV 역묘화약물전정기출.
The host cells invaded by hepatitis C virus(HCV) is such complicated process that can only be ac?complished under the mediation of various receptors. Some cell receptors reported may have some relations to HCV such as CD81, low density lipoprotein receptor, scavenger receptor class B type Ⅰ, tight-junction proteins, epidermal growth factor receptor, Ephrin receptor A2, Niemann-Pick C1-like 1 cholesterol absorption receptor. These thesis gives a detailed introduction of them, which could possibly make a foundation for searching new types of HCV vaccine and exploring antiviral medicine.