CAJ | 학술논문

目的:研究体外循环心脏不停跳心内直视手术对肾功能的影响,比较心脏停跳和不停跳两种手术方法对肾功能的影响.方法:选择40例接受二尖瓣置换术的患者,随机分为心脏停跳组和不停跳组,分别于术前、转机30min、术后1h、术后24h、术后72h 取静脉血,检测胱抑素 C 和白介素-18水平.结果:体外循环术后患者血清胱抑素 C 和白介素18水平较术前均有升高(P<0.05),不停跳组胱抑素 C 和白介素18的升高较停跳组低(P<0.05),且恢复较快.结论:浅低温体外循环心脏不停跳心内直视手术对肾功能有影响,但较心脏停跳的体外循环手术小.
목적:연구체외순배심장불정도심내직시수술대신공능적영향,비교심장정도화불정도량충수술방법대신공능적영향.방법:선택40례접수이첨판치환술적환자,수궤분위심장정도조화불정도조,분별우술전、전궤30min、술후1h、술후24h、술후72h 취정맥혈,검측광억소 C 화백개소-18수평.결과:체외순배술후환자혈청광억소 C 화백개소18수평교술전균유승고(P<0.05),불정도조광억소 C 화백개소18적승고교정도조저(P<0.05),차회복교쾌.결론:천저온체외순배심장불정도심내직시수술대신공능유영향,단교심장정도적체외순배수술소.
@@@@Objective: To study the effect on kidneys of peoples who have the open heart surgery under cardiopulmonary bypass(CPB) with a beating heart and discuss the difference of effects on renal function between CPB with a beating and stopping heart. Methods: Detecting the content of Cystatin C and Interleukin 18 in venous blood got from 40 patients, divided into CPB with beating heart group and CPB with stopping heart group randomly, in the time of 1h before operation, 30min after the beginning of CPB, 1h after operation, 24h after operation and 72h after operation. Results: After CPB, the content of Cystatin C and Interleukin 18 in patient's serum is increased(P<0.05), but the increase of beating heart group is lower and faster to recover then stopping heart group(P<0.05). Conclusion: open heart surgery under CPB with beating heart wil impact renal function, but this impact is smaler than CPB with a stopping heart leading to.