药品评价
藥品評價
약품평개
DRUG REEVALUATION
2013年
8期
40-41
,共2页
洋地黄中毒%合并用药%血药浓度监测
洋地黃中毒%閤併用藥%血藥濃度鑑測
양지황중독%합병용약%혈약농도감측
Digitalis Intoxication%Drug Combination%Therapeutic Drug Monitoring
一患者在使用常规剂量去乙酰毛花苷治疗过程中,因合并使用托拉塞米、胺碘酮、抗菌药物等多种药物,加之患者高龄、肾功能不全等因素,导致发生患者洋地黄中毒.因此,在临床实践中,对于使用洋地黄类药物的患者,应注意监护患者合并用药情况及其生理、病理状况,及时监测血药浓度并调整用药方案,避免中毒事件的发生.
一患者在使用常規劑量去乙酰毛花苷治療過程中,因閤併使用託拉塞米、胺碘酮、抗菌藥物等多種藥物,加之患者高齡、腎功能不全等因素,導緻髮生患者洋地黃中毒.因此,在臨床實踐中,對于使用洋地黃類藥物的患者,應註意鑑護患者閤併用藥情況及其生理、病理狀況,及時鑑測血藥濃度併調整用藥方案,避免中毒事件的髮生.
일환자재사용상규제량거을선모화감치료과정중,인합병사용탁랍새미、알전동、항균약물등다충약물,가지환자고령、신공능불전등인소,도치발생환자양지황중독.인차,재림상실천중,대우사용양지황류약물적환자,응주의감호환자합병용약정황급기생리、병리상황,급시감측혈약농도병조정용약방안,피면중독사건적발생.
@@@@ Digitalis intoxication occurred in a patient who was given conventional dose of deslanoside in combination with torasemide, amiodarone, and antibacterial drugs. In addition, the elderly patient had impaired kidney function which also contributed to the occurrence of digitalis intoxication. Therefore, pharmacists are suggested to pay more attention to the combined use of drugs and patient’s physiologic and pathologic conditions in clinical practice. It is important to monitor the blood digoxin concentration and modify the dosage of digitaloid drugs in time to prevent digoxin-related intoxication.
