CAJ | 학술논문

目的运用弥散张量成像(DTI)定量研究不同血压水平的变化对无症状中年人脑白质部位的各向异性特点.方法选择临床无症状中年人60名,按血压水平分为3组,均行DTI检查.分析其表面弥散系数(ADC)图及各向异性分数(FA)图的特点,并对各组相同部位脑白质进行ADC值及FA值行定量分析,通过统计学分析得出其弥散系数和各向异性特点.结果 DTI可清晰显示脑内白质的走行及方向.不同血压水平对相同年龄组相同解剖部位脑白质ADC值及FA值的差异有统计学意义.FA值能准确定量分析无症状正常人脑白质部位的各向异性特点.结论血压的升高,可造成脑血管的缓慢损伤.即使在无症状中年人中,微小的血管性脑损伤也可在生活中隐匿性发生,并产生明显的影像学效应.研究强调了早期控制血压达标的重要性.
목적운용미산장량성상(DTI)정량연구불동혈압수평적변화대무증상중년인뇌백질부위적각향이성특점.방법선택림상무증상중년인60명,안혈압수평분위3조,균행DTI검사.분석기표면미산계수(ADC)도급각향이성분수(FA)도적특점,병대각조상동부위뇌백질진행ADC치급FA치행정량분석,통과통계학분석득출기미산계수화각향이성특점.결과 DTI가청석현시뇌내백질적주행급방향.불동혈압수평대상동년령조상동해부부위뇌백질ADC치급FA치적차이유통계학의의.FA치능준학정량분석무증상정상인뇌백질부위적각향이성특점.결론혈압적승고,가조성뇌혈관적완만손상.즉사재무증상중년인중,미소적혈관성뇌손상야가재생활중은닉성발생,병산생명현적영상학효응.연구강조료조기공제혈압체표적중요성.
Objective To evaluate the effects of on increasing blood pressure on white-matter integrity in asymptomatic young adults with diffusion tensor imaging technology. Methods Sixty asymptomatic young adults were divided to normal group, prehypertension group and hypertension group according to their blood pressure levels. The ADC values and FA values were measured. We analysed diffusiom tensor imaging measures of fractional anisotropy and mean diffusivity. And the statistical analysis data was to establish. Results DTI could display the cerebral white matter fibers well. There were statistical differences among FA values and ADC values of different groups. FA values can be used to analyze the anisotropy of cerebral white matter fibers of different adults groups quantitatively. Conclusion Increased blood pressure is associated with clinically concomitant subtle brain injuries,even for asymptomatic young adults. Our results emphasise the need for early and optimun control of blood pressure.