CAJ | 학술논문

目的:探讨影响肝门部胆管癌术后疗效的手术治疗策略.方法:对2007年1月-2012年1月笔者所在医院通过手术治疗的45例肝门部胆管癌进行回顾性分析.其中单纯探查组3例,置管外引流组15例,胆肠内引流组13例,根治性切除组14例,比较各组术后生存时间.结果:3例患者经探查后发现已失去进一步手术机会,相继于术后1~3周发生肝功能衰竭而死亡.置管外引流组平均生存时间为11.5个月;胆肠内引流组平均生存时间为15.4个月;根治性切除组平均生存时间为22个月.根治性切除组与引流组术后生存时间比较差异有统计学意义(P<0.05).结论:对于无法根治的肝门部胆管癌患者,姑息性肿瘤切除和引流术也可以延长患者的生命.根治性切除仍然是治疗肝门部胆管癌的首选方法.
목적:탐토영향간문부담관암술후료효적수술치료책략.방법:대2007년1월-2012년1월필자소재의원통과수술치료적45례간문부담관암진행회고성분석.기중단순탐사조3례,치관외인류조15례,담장내인류조13례,근치성절제조14례,비교각조술후생존시간.결과:3례환자경탐사후발현이실거진일보수술궤회,상계우술후1~3주발생간공능쇠갈이사망.치관외인류조평균생존시간위11.5개월;담장내인류조평균생존시간위15.4개월;근치성절제조평균생존시간위22개월.근치성절제조여인류조술후생존시간비교차이유통계학의의(P<0.05).결론:대우무법근치적간문부담관암환자,고식성종류절제화인류술야가이연장환자적생명.근치성절제잉연시치료간문부담관암적수선방법.
Objective:To assess the therapeutic strategies and prognostic factors that could influence the clinical out-come of hilar cholangiocarcinoma(HCC).Method:A retrospective study was conducted on 45 cases of HCC.Including,Exploration of operation 3 cases,Catheter drainage group 15 cases,Biliary enteric drainage group 13 cases,14 cases of radical resection group.The groups were compared the postoperative survival time.Result:3 cases lost the chance of operation after the exploration,1 or 3 weeks later they died of hepatic failure.Catheter drainage group mean survival time of 11.5 months:biliary enteric anastomosis group the mean survival time of 15.4 months:radical resection group the mean survival time of 22 months. The difference that Radical resection group and drainage group postoperative survival time compared was statistically significant.Conclusion:Palliative resection or drainage procedures can effectively prolong the incurable patient's life.Radical resection is the treatment choice for hilar cholangiocarcinoma.