CAJ | 학술논문

目的:研究地佐辛对结肠癌根治术后罗哌卡持续切口镇痛作用的影响.方法:将40例择期行结肠癌根治术的患者随机分为地佐辛复合罗哌卡组(D组)和罗哌卡组(R组),手术结束后,进行切口局部浸润并放置渗透导管,D组经切口持续给予0.2%罗哌卡(内含地佐辛54μg/mL),R组给予0.2%罗哌卡.结果:D组术后12 h、24 h和48 h咳嗽和休息时VAS评分低R组(P<0.05),R组48 h内镇痛泵按压次数及舒芬太尼使用量明显高D组(P<0.05),恶心呕吐及嗜睡发生率R组高D组(P<0.05).肠蠕动恢复时间及术后离床时间,D组早R组(P<0.05).两组患者术后切口愈合良好,无1例发生切口感染.结论:地佐辛增强罗哌卡术后持续切口镇痛的效果,有利患者的术后早期恢复.
목적:연구지좌신대결장암근치술후라고잡지속절구진통작용적영향.방법:장40례택기행결장암근치술적환자수궤분위지좌신복합라고잡조(D조)화라고잡조(R조),수술결속후,진행절구국부침윤병방치삼투도관,D조경절구지속급여0.2%라고잡(내함지좌신54μg/mL),R조급여0.2%라고잡.결과:D조술후12 h、24 h화48 h해수화휴식시VAS평분저R조(P<0.05),R조48 h내진통빙안압차수급서분태니사용량명현고D조(P<0.05),악심구토급기수발생솔R조고D조(P<0.05).장연동회복시간급술후리상시간,D조조R조(P<0.05).량조환자술후절구유합량호,무1례발생절구감염.결론:지좌신증강라고잡술후지속절구진통적효과,유리환자적술후조기회복.
Objective To study the analgesic efficacy of continuous wound infusion of Ropivacaine with Dezocine for abdominal colorectal surgery. Methods A randomized, participant and outcome assessor-blind?ed, placebo-controlled trial was performed on 40 patients presenting for major abdominal colorectal surgery from June 2010 to May 2012. Patients were allocated to receive ropivacaine 0.2% in conjunction with Dezocine or Ropivacaine 0.2% via a dual catheter Painbuster Soaker continuous infusion device into their midline laparoto?my wound for 48 hours postoperatively. Results The continuous wound infusion of ropivacaine in conjunction with Dezocine after abdominal colorectal surgery conveys greater benefit compared with sole Ropivacaine wound infusion, statistically significant differences could be shown for: VAS scale, morphine usage, mobility, nausea, or recovery time of bowel function. Conclusion Management of pain after major abdominal colorectal surgery is best achieved through adopting a continuous wound infusion of Ropivacaine in conjunction with Dezocine.