CAJ | 학술논문

目的:探讨香砂六君子汤加减治疗幽门螺杆菌(Hp)相关性胃炎的临床疗效.方法:采用随机数字表法将109例Hp相关性胃炎患者分为两组,西药组予质子泵抑制剂三联法配合胃粘膜保护剂,中药组予香砂六君子汤加减,2周为1个疗程,3个疗程结束后对比临床疗效和安全性.结果:中药组总有效率92.73%明显优西药组75.93%,P<0.05;中药组Hp清除率90.91%明显优西药组72.22%,P<0.05;中药组不良反应发生率3.64%明显低西药组18.52%,P<0.05.结论:香砂六君子汤加减能够明显改善Hp相关性胃炎的临床症状和体征,Hp清除率高,安全可靠,值得临床在中药治疗Hp相关性胃炎方面继续研究.
목적:탐토향사륙군자탕가감치료유문라간균(Hp)상관성위염적림상료효.방법:채용수궤수자표법장109례Hp상관성위염환자분위량조,서약조여질자빙억제제삼련법배합위점막보호제,중약조여향사륙군자탕가감,2주위1개료정,3개료정결속후대비림상료효화안전성.결과:중약조총유효솔92.73%명현우서약조75.93%,P<0.05;중약조Hp청제솔90.91%명현우서약조72.22%,P<0.05;중약조불량반응발생솔3.64%명현저서약조18.52%,P<0.05.결론:향사륙군자탕가감능구명현개선Hp상관성위염적림상증상화체정,Hp청제솔고,안전가고,치득림상재중약치료Hp상관성위염방면계속연구.
Objective: To investigate the clinical effect of modified Xiangsha Liujunzi decoction on gastritis related with helicobacter pylori. Methods:109 patients were randomly divided into two groups. The modern medicine group was given trigeminy with proton pump inhibitor combined with gastric mucosa protectant, while the TCM group was given modified Xiangsha Liujunzi decoction. Results: The total effective rate in the TCM group was 92.73%, significantly higher than that in the modern medicine group 75.93%(P<0.05). The HP clearance rate in the TCM group was 90.91%, significantly higher than that in the modern medicine group 72.22%(P<0.05). The adverse effect incidence in the TCM group was 3.64%, significantly lower than that in the modern medicine group 18.52%(P<0.05). Conclusion: Modified Xiangsha Liujunzi decoction was significantly effective on treating gastritis related with helicobacter pylori.