当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2013年
12期
150-151
,共2页
曲美他嗪%慢性心力衰竭%血浆脑钠肽%心功能
麯美他嗪%慢性心力衰竭%血漿腦鈉肽%心功能
곡미타진%만성심력쇠갈%혈장뇌납태%심공능
Trimetazidine%Chronic heart failure%Brain natriuretic peptide%Heart function
目的探讨曲美他嗪对慢性心力衰竭患者血浆脑钠肽(BNP)水平及心功能的影响.方法选取安徽省利辛县人民医院2009年3月~2012年3月100例慢性心力衰竭的患者,均在常规治疗基础上给予曲美他嗪治疗,观察对比治疗前后患者血浆BNP水平和NYHA心功能分级、心电图评价心功能指标的变化.结果治疗后患者血浆BNP水平,心功能指标左心室射血分数、心脏指数、心搏出量、每搏输出量与治疗前相比均明显改善(P<0.05).结论应用曲美他嗪治疗慢性心力衰竭效果明显,有利于病情转归.
目的探討麯美他嗪對慢性心力衰竭患者血漿腦鈉肽(BNP)水平及心功能的影響.方法選取安徽省利辛縣人民醫院2009年3月~2012年3月100例慢性心力衰竭的患者,均在常規治療基礎上給予麯美他嗪治療,觀察對比治療前後患者血漿BNP水平和NYHA心功能分級、心電圖評價心功能指標的變化.結果治療後患者血漿BNP水平,心功能指標左心室射血分數、心髒指數、心搏齣量、每搏輸齣量與治療前相比均明顯改善(P<0.05).結論應用麯美他嗪治療慢性心力衰竭效果明顯,有利于病情轉歸.
목적탐토곡미타진대만성심력쇠갈환자혈장뇌납태(BNP)수평급심공능적영향.방법선취안휘성리신현인민의원2009년3월~2012년3월100례만성심력쇠갈적환자,균재상규치료기출상급여곡미타진치료,관찰대비치료전후환자혈장BNP수평화NYHA심공능분급、심전도평개심공능지표적변화.결과치료후환자혈장BNP수평,심공능지표좌심실사혈분수、심장지수、심박출량、매박수출량여치료전상비균명현개선(P<0.05).결론응용곡미타진치료만성심력쇠갈효과명현,유리우병정전귀.
@@@@Objective To study the effect of trimetazidine in chronic heart failure patients on plasma brain natriuretic peptide ( BNP ) level and cardiac function in rats. Methods From March 2009 to March 2012 100 cases of chronic heart failure patients were chosen, the patients were given trimetazidine treatment on the basis of routine treatment, the level of plasma BNP and NYHA grade of heart function, ECG in the evaluation of cardiac function indexes were observed and compared before and after treatment. Results After treatment, the plasma BNP level in patients with heart function index, left ventricular ejection fraction, cardiac index stroke volume, stroke volume compared with those before treatment were significantly improved (P<0.05). Conclusion The application of trimetazidine in treatment of chronic heart failure with obvious effect, is conducive to disease outcome.
