CAJ | 학술논문

局部晚期直肠癌的治疗已经形成放疗、化疗联合手术切除的多学科综合治疗的模式.NCCN指南推荐的局部晚期直肠癌综合治疗的最佳顺序是新辅助短程放疗或新辅助同步放化疗后接受全直肠系膜切除手术,随后4个月的辅助化疗.新辅助治疗可以使肿瘤降期、降级,达到提高根治性切除率、减少局部复发和增加保肛率的目的.但是随着晚期治疗中更高疗效药物的出现以及对生活质量的重视,个体化治疗成为未来研究的方向.
국부만기직장암적치료이경형성방료、화료연합수술절제적다학과종합치료적모식.NCCN지남추천적국부만기직장암종합치료적최가순서시신보조단정방료혹신보조동보방화료후접수전직장계막절제수술,수후4개월적보조화료.신보조치료가이사종류강기、강급,체도제고근치성절제솔、감소국부복발화증가보항솔적목적.단시수착만기치료중경고료효약물적출현이급대생활질량적중시,개체화치료성위미래연구적방향.
@@@@The treatment of the local y advanced rectal cancer had entered the multimodel treatment combined with radiotherapy, chemotherapy and surgery. NCCN guidelines recommended the best sequence is neoadjuvant short-course radiotherapy or concurrent chemoradiotherapy, then total mesorectal excision, thereafter four months of adjuvant chemotherapy. Neoadjuvant therapy can make tumor down-stage and degradation, improve the radical resection, reduce the local recurrence and increase the sphincter preservation. But with the advent of more effective drugs and the emphasize on the quality of life, the individualized therapy for rectal cancer has become the keypoint in the future research.