生物技术进展
生物技術進展
생물기술진전
2013年
2期
140-144
,共5页
多孔木霉菌%形态分化%生理分化%环孢菌素A
多孔木黴菌%形態分化%生理分化%環孢菌素A
다공목매균%형태분화%생리분화%배포균소A
Tolypocladium niveum%morphological differentiation%physiological differentiation%cyclosporin A
通过对多孔木霉菌在产孢培养基和产菌丝培养基发酵情况的比较,并对整个发酵过程的菌丝形态进行观察,分析多孔木霉菌的菌丝形态分化与环孢菌素A合成的关系.研究表明,环孢菌素A的合成与多孔木霉菌的形态分化密切相关,膨大的菌丝与孢子相互转化过程中,更有利于环孢菌素A的合成.
通過對多孔木黴菌在產孢培養基和產菌絲培養基髮酵情況的比較,併對整箇髮酵過程的菌絲形態進行觀察,分析多孔木黴菌的菌絲形態分化與環孢菌素A閤成的關繫.研究錶明,環孢菌素A的閤成與多孔木黴菌的形態分化密切相關,膨大的菌絲與孢子相互轉化過程中,更有利于環孢菌素A的閤成.
통과대다공목매균재산포배양기화산균사배양기발효정황적비교,병대정개발효과정적균사형태진행관찰,분석다공목매균적균사형태분화여배포균소A합성적관계.연구표명,배포균소A적합성여다공목매균적형태분화밀절상관,팽대적균사여포자상호전화과정중,경유리우배포균소A적합성.
The relationship between morphological differentiation and cyclosporin A synthesis in fermentation process of Tolypocladium niveum CA411 was studied. The mycelium and spore morphology changes were observed while Tolypocladium niveum were inoculated in mycelium and sporulation media under the optical microscope. The cyclosporin A synthesis was highly related with morphological differentiation. It's more conducive to the synthesis of cyclosporin A during the process of filamentous hyphae into spore.
