中国癌症防治杂志
中國癌癥防治雜誌
중국암증방치잡지
CHINESE JOURNAL OF ONCOLOGY PREVENTION AND TREATMENT
2013年
1期
61-64
,共4页
左朝晖%张理%欧阳永忠%汤明%林劲冠%肖华%邱晓昕%潘曙光%尹彬%罗威%李俊军%朱海珍
左朝暉%張理%歐暘永忠%湯明%林勁冠%肖華%邱曉昕%潘曙光%尹彬%囉威%李俊軍%硃海珍
좌조휘%장리%구양영충%탕명%림경관%초화%구효흔%반서광%윤빈%라위%리준군%주해진
胃肿瘤%进展期胃癌%联合脏器切除%新辅助化疗%综合治疗
胃腫瘤%進展期胃癌%聯閤髒器切除%新輔助化療%綜閤治療
위종류%진전기위암%연합장기절제%신보조화료%종합치료
Gastric neoplasms%Locally advanced gastric cancer%Combined multiple organ resection%Preoperative neoadjuvant chemotherapy%Comprehensive treatment
目的探讨联合脏器切除术治疗局部进展期胃癌的临床疗效及预后.方法对我院2002年8月至2009年12月收治的93例局部侵犯周围脏器的进展期胃癌患者的临床资料进行回顾性分析.结果联合胰体尾及脾切除24例,脾切除17例,横结肠部分切除10例,左肝外叶切除10例,胆囊切除7例,膈肌部分切除5例,胰体尾及脾切除加横结肠部分切除5例,双侧卵巢切除5例,左肝外叶及横结肠切除4例,胰十二指肠切除3例,肾上腺切除2例,联合胰体尾、脾、左肝外叶、部分膈肌及左肾上腺切除1例.术前新辅助化疗25例(26.88%),术后病理肿瘤缓解分级评分:0级4例,1级6例,2级8例,3级5例,4级2例,缓解率为84.0%.术后并发症发生率为31.18%,死亡率为4.30%,1年、3年生存率分别为50.11%和26.12%.结论联合脏器切除术是治疗局部进展期胃癌有效的手段,可提高术后生存率.术前辅助化疗能在一定程度上提高手术切除率和术后生存率.
目的探討聯閤髒器切除術治療跼部進展期胃癌的臨床療效及預後.方法對我院2002年8月至2009年12月收治的93例跼部侵犯週圍髒器的進展期胃癌患者的臨床資料進行迴顧性分析.結果聯閤胰體尾及脾切除24例,脾切除17例,橫結腸部分切除10例,左肝外葉切除10例,膽囊切除7例,膈肌部分切除5例,胰體尾及脾切除加橫結腸部分切除5例,雙側卵巢切除5例,左肝外葉及橫結腸切除4例,胰十二指腸切除3例,腎上腺切除2例,聯閤胰體尾、脾、左肝外葉、部分膈肌及左腎上腺切除1例.術前新輔助化療25例(26.88%),術後病理腫瘤緩解分級評分:0級4例,1級6例,2級8例,3級5例,4級2例,緩解率為84.0%.術後併髮癥髮生率為31.18%,死亡率為4.30%,1年、3年生存率分彆為50.11%和26.12%.結論聯閤髒器切除術是治療跼部進展期胃癌有效的手段,可提高術後生存率.術前輔助化療能在一定程度上提高手術切除率和術後生存率.
목적탐토연합장기절제술치료국부진전기위암적림상료효급예후.방법대아원2002년8월지2009년12월수치적93례국부침범주위장기적진전기위암환자적림상자료진행회고성분석.결과연합이체미급비절제24례,비절제17례,횡결장부분절제10례,좌간외협절제10례,담낭절제7례,격기부분절제5례,이체미급비절제가횡결장부분절제5례,쌍측란소절제5례,좌간외협급횡결장절제4례,이십이지장절제3례,신상선절제2례,연합이체미、비、좌간외협、부분격기급좌신상선절제1례.술전신보조화료25례(26.88%),술후병리종류완해분급평분:0급4례,1급6례,2급8례,3급5례,4급2례,완해솔위84.0%.술후병발증발생솔위31.18%,사망솔위4.30%,1년、3년생존솔분별위50.11%화26.12%.결론연합장기절제술시치료국부진전기위암유효적수단,가제고술후생존솔.술전보조화료능재일정정도상제고수술절제솔화술후생존솔.
@@@@Objective To investigate clinical outcomes and prognosis for patients undergoing multiple organ resection to treat locally advanced gastric cancer. Methods We retrospectively analyzed 93 patients with locally advanced gastric cancer who underwent multi-ple organ resection in our hospital between January 2002 and December 2009. Results Of the 93 patients,24 underwent distal pan-createctomy and splenectomy;17,splenectomy;10,transverse colectomy;10,left hepatectomy;7,cholecystectomy;5,diaphragmatic re-section;5,splenectomy;5,distal pancreatectomy plus transverse colectomy;5,double oopherectomy;4,left hepatectomy plus transverse colectomy;3,pancreatoduodenectomy;2,auxiliary adrenalectomy;and 1,distal pancreatectomy,splenectomy,left hepatectomy,diaphrag-matic resection and auxiliary adrenalectomy.The overall preoperative neoadjuvant chemotherapy rate was 25/93(26.88%),and tumor release grades were distributed as follows:grade 0,4 patients;grade 1,6 patients;grade 2,8 patients;grade 3,5 patients;and grade 4,2 patients.Postoperative morbidity and mortality rates were,respectively,29/93(31.18%)and 4/93(4.30%).The 1- and 3-year overall survival rates were 50.11% and 26.12%,respectively. Conclusions Multiple organ resection is an effective treatment for locally ad-vanced gastric cancer and it improves survival rates. Preoperative neoadjuvant chemotherapy improves survival and resection rates.
