CAJ | 학술논문

目的探讨精液沙眼衣原体感染对精子透明质酸酶(HYD)活性的影响.方法选择精液沙眼衣原体阳性男性不育83例作为沙眼衣原体阳性组,另选择正常对照组35例.检测精液常规,免疫层析法检测沙眼衣原体感染情况,精子HYD活性采用药盒检测.结果沙眼衣原体阳性组精子HYD活性(27±17)μm,HYD阳性率(53±19)%;正常对照组精子HYD活性(38±16)μm,HYD阳性率(71±19)%,沙眼衣原体阳性组HYD活性和HYD阳性率均较正常对照组明显偏低(P<0.01).结论精液CT感染导致精子HYD活性减弱是导致男性不育的机制之一.
목적탐토정액사안의원체감염대정자투명질산매(HYD)활성적영향.방법선택정액사안의원체양성남성불육83례작위사안의원체양성조,령선택정상대조조35례.검측정액상규,면역층석법검측사안의원체감염정황,정자HYD활성채용약합검측.결과사안의원체양성조정자HYD활성(27±17)μm,HYD양성솔(53±19)%;정상대조조정자HYD활성(38±16)μm,HYD양성솔(71±19)%,사안의원체양성조HYD활성화HYD양성솔균교정상대조조명현편저(P<0.01).결론정액CT감염도치정자HYD활성감약시도치남성불육적궤제지일.
Objective To study the effect of chlamydia trachomatis infection on the hyaluronidase (HYD) reactive of sperm. Methods 83 cases with chlamydia trachomatis positive and male infertive were chosen as chlamydia trachomatis positive group , and 35 cases of normal control group. Inspection semen routine,detection of chlamydia trachomatis: immunochromatography. We analyzed the HYD reactive of sperm by the way of kit. Results The sperm’s HYD reactive and positive rate of the chlamydia trachomatis positive group were respectively (27 ± 17)μm and (53 ± 19)%, those of the normal control group were respectively (38 ± 16)μm and (71 ± 19)%. The sperm’s HYD reactive and positive rate of chlamydia trachomatis positive group obviously lower than that of control group (P<0.01). Conclusion The chlamydia trachomatis infecton weakens HYD reactive of sperm which causes infertile.Therefore, chlamydia trachomatis infection in semen is one of the most important mechanisms of male infertility.