CAJ | 학술논문

脊髓小脑性共济失调3型(SCA3)是遗传性脊髓小脑性共济失调最常见的亚型,发病方式可呈家族性,也可呈散发性,主要通过临床表现及基因检测确诊.目前无特效药物,临床治疗以延缓病情发展和对症治疗为主.随着人们生活水平的提高,该疾病越来越受到研究者的重视,现就近年来SCA3/MJD发病机制、临床特点、治疗进展进行系统的阐述.
척수소뇌성공제실조3형(SCA3)시유전성척수소뇌성공제실조최상견적아형,발병방식가정가족성,야가정산발성,주요통과림상표현급기인검측학진.목전무특효약물,림상치료이연완병정발전화대증치료위주.수착인문생활수평적제고,해질병월래월수도연구자적중시,현취근년래SCA3/MJD발병궤제、림상특점、치료진전진행계통적천술.
Spinocerebellar ataxia type 3 is the most common subtype in Hereditary spinocerebellar ataxia,it begin with a familial,and can also be sporadic,it is Mainly diagnosed by clinical presentation and genetic testing. Now, there is no particular drug to control it,it is usually treated it by delaying its development and Symptomatic treatment, in order to Improving the self-care ability of the patients.With the development of people”s live standard,it become increasingly concentrated by researchers. Now, I will summarize hepathogenesis, clinical features, treatment progress of the SCA3/MJD.