中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2013年
3期
496-500
,共5页
司庆宗%安晓莉%安应飞%刘斌
司慶宗%安曉莉%安應飛%劉斌
사경종%안효리%안응비%류빈
生物材料%生物材料综述%超高分子量聚乙烯%人工关节假体%摩擦磨损机制%磨屑%其他基金
生物材料%生物材料綜述%超高分子量聚乙烯%人工關節假體%摩抆磨損機製%磨屑%其他基金
생물재료%생물재료종술%초고분자량취을희%인공관절가체%마찰마손궤제%마설%기타기금
biomaterials%biomaterial review%ultra-high molecular weight polyethylene%artificial joint prosthetics%friction and wear mechanisms%debris%other grants-supported paper
背景:超高分子量聚乙烯因其自身优良的理化性能而被广泛应用于医学领域中的人工关节置换.目的:概述医用超高分子量聚乙烯应用于人工关节假体的摩擦磨损性能及其改性研究进展.方法:以“超高分子量聚乙烯、人工关节假体、摩擦磨损机制、摩削”;“Ultra-High Molecular Weight Polyethylene,UHMWPE,artificial joint prosthetics,mechanism of friction and wear,wear debris”为关键词,检索1970至2012年 ISI 数据库、PubMed 数据库,1979至2012年 CNKI 数据库、万方数据库及维普科技期刊数据库中有关医用超高分子量聚乙烯作为人工关节假体的自身摩擦磨损及改性研究.结果与结论:研究证实超高分子量聚乙烯的主要摩擦磨损机制为磨粒磨损、黏附磨损和疲劳磨损.针对其低耐摩擦性能,目前实验室可以通过无机填料改性法,包括羟基磷灰石、氧化锆、炭黑、碳纤维、碳纳米管等,交联法包括有机硅氧烷偶联剂交联和各种离子辐射等方法进行改性,并在各种模拟环境下所进行的摩擦磨损测试,结果证明这些改性后的材料耐磨性能均得到了不同程度提高.对医用超高分子量聚乙烯应用于人工关节假体的摩擦磨损实验研究体系主要包括摩擦磨损模拟试验机、润滑体液、磨损、磨屑的测定和评价等.
揹景:超高分子量聚乙烯因其自身優良的理化性能而被廣汎應用于醫學領域中的人工關節置換.目的:概述醫用超高分子量聚乙烯應用于人工關節假體的摩抆磨損性能及其改性研究進展.方法:以“超高分子量聚乙烯、人工關節假體、摩抆磨損機製、摩削”;“Ultra-High Molecular Weight Polyethylene,UHMWPE,artificial joint prosthetics,mechanism of friction and wear,wear debris”為關鍵詞,檢索1970至2012年 ISI 數據庫、PubMed 數據庫,1979至2012年 CNKI 數據庫、萬方數據庫及維普科技期刊數據庫中有關醫用超高分子量聚乙烯作為人工關節假體的自身摩抆磨損及改性研究.結果與結論:研究證實超高分子量聚乙烯的主要摩抆磨損機製為磨粒磨損、黏附磨損和疲勞磨損.針對其低耐摩抆性能,目前實驗室可以通過無機填料改性法,包括羥基燐灰石、氧化鋯、炭黑、碳纖維、碳納米管等,交聯法包括有機硅氧烷偶聯劑交聯和各種離子輻射等方法進行改性,併在各種模擬環境下所進行的摩抆磨損測試,結果證明這些改性後的材料耐磨性能均得到瞭不同程度提高.對醫用超高分子量聚乙烯應用于人工關節假體的摩抆磨損實驗研究體繫主要包括摩抆磨損模擬試驗機、潤滑體液、磨損、磨屑的測定和評價等.
배경:초고분자량취을희인기자신우량적이화성능이피엄범응용우의학영역중적인공관절치환.목적:개술의용초고분자량취을희응용우인공관절가체적마찰마손성능급기개성연구진전.방법:이“초고분자량취을희、인공관절가체、마찰마손궤제、마삭”;“Ultra-High Molecular Weight Polyethylene,UHMWPE,artificial joint prosthetics,mechanism of friction and wear,wear debris”위관건사,검색1970지2012년 ISI 수거고、PubMed 수거고,1979지2012년 CNKI 수거고、만방수거고급유보과기기간수거고중유관의용초고분자량취을희작위인공관절가체적자신마찰마손급개성연구.결과여결론:연구증실초고분자량취을희적주요마찰마손궤제위마립마손、점부마손화피로마손.침대기저내마찰성능,목전실험실가이통과무궤전료개성법,포괄간기린회석、양화고、탄흑、탄섬유、탄납미관등,교련법포괄유궤규양완우련제교련화각충리자복사등방법진행개성,병재각충모의배경하소진행적마찰마손측시,결과증명저사개성후적재료내마성능균득도료불동정도제고.대의용초고분자량취을희응용우인공관절가체적마찰마손실험연구체계주요포괄마찰마손모의시험궤、윤활체액、마손、마설적측정화평개등.
@@@@BACKGROUND: Ultra-high molecular weight polyethylene has been used widely for the artificial joint prosthetics due to its excel ent physical and chemical properties, which includes the hip and knee joint in the medicine field. OBJECTIVE: To summarize the progress in the modification and tribological studies of medical ultra-high molecular weight polyethylene in recent years. METHODS: The literatures, regarding to the modification and tribological studies of medical ultra-high molecular weight polyethylene, were searched by a computer in ISI and PubMed databases from 1970 to 2012 as wel as in CNKI, Wanfang and VIP database from 1979 to 2012, respectively. The keywords were “ultra-high molecular weight polyethylene, UHMWPE, artificial joint prosthetics, mechanism of friction and wear, wear debris” in English and Chinese, respectively. The repetitive researches were excluded. RESULTS AND CONCLUSION: The results prove that the abrasive wear, adhesion wear and fatigue wear are the main mechanisms of ultra-high molecular weight polyethylene. Because of its low wear resistance, many methods have been used to enhance its tribological properties, including inorganic fil ing (such as hydroxyapatite, zirconium oxide, carbon black, carbon fiber, carbon nanotubes), and the crosslinking (such as organic silane coupling and variety of ionizing radiations). Moreover, the results demonstrate that the wear resistance of the modified materials was improved to different extents in al kinds of joint simulator environment. This paper also expounds the friction mechanism and some wear means of ultra-high molecular weight polyethylene, such as joint simulator, lubrication system, the measurement and evaluation of wear and wear debris.