CAJ | 학술논문

生物材料%生物材料学术探讨%口腔%银%抗菌%材料%纳米%病原菌%变形链球菌%乳酸杆菌%粘性放线菌%白色念珠菌%牙龈卟啉单胞菌%金黄色葡萄球菌%大肠埃希菌生物材料%生物材料學術探討%口腔%銀%抗菌%材料%納米%病原菌%變形鏈毬菌%乳痠桿菌%粘性放線菌%白色唸珠菌%牙齦卟啉單胞菌%金黃色葡萄毬菌%大腸埃希菌
생물재료%생물재료학술탐토%구강%은%항균%재료%납미%병원균%변형련구균%유산간균%점성방선균%백색념주균%아간계람단포균%금황색포도구균%대장애희균
biomaterials%oral cavity%silver%antibacterial%materials%nano%pathogens%Streptococcus mutans%Lactobacilli%Actinomyces viscosus%Candida albicans%Porphyromonas gingivalis Aeromonas%Staphylococcus aureus%Escherichia coli

背景:纳米载银无机抗菌剂具有抗菌谱广、抗菌能力强等特点,是目前口腔无机抗菌材料研究的热点之一.目的:研究纳米载银无机抗菌材料的抗菌性能及抗菌机制,为基础实验研究和临床应用提供参考信息.方法:研究多种口腔纳米载银无机抗菌材料对常见病原菌如变形链球菌、白色念珠菌以及粘性放线菌等的抗菌性能,其中包括最低杀菌浓度以及抗菌率等,同时进行对比分析.并且研究纳米载银无机抗菌材料的抗菌机制,明确其优点与不足.结果与结论:口腔纳米载银无机抗菌材料具有较广的抗菌谱,对变形链球菌、乳酸杆菌、粘性放线菌、白色念珠菌、牙龈卟啉单胞菌、金黄色葡萄球菌以及大肠埃希菌等均具有较强的抗菌性能,最低杀菌浓度较低,而抗菌率较高.但是同一纳米载银无机抗菌材料对不同的病原菌,其最低杀菌浓度不同,抗菌率也不同,而不同的纳米载银无机抗菌材料对同一病原菌的最低杀菌浓度也不相同,抗菌率也不同.
배경:납미재은무궤항균제구유항균보엄、항균능력강등특점,시목전구강무궤항균재료연구적열점지일.목적:연구납미재은무궤항균재료적항균성능급항균궤제,위기출실험연구화림상응용제공삼고신식.방법:연구다충구강납미재은무궤항균재료대상견병원균여변형련구균、백색념주균이급점성방선균등적항균성능,기중포괄최저살균농도이급항균솔등,동시진행대비분석.병차연구납미재은무궤항균재료적항균궤제,명학기우점여불족.결과여결론:구강납미재은무궤항균재료구유교엄적항균보,대변형련구균、유산간균、점성방선균、백색념주균、아간계람단포균、금황색포도구균이급대장애희균등균구유교강적항균성능,최저살균농도교저,이항균솔교고.단시동일납미재은무궤항균재료대불동적병원균,기최저살균농도불동,항균솔야불동,이불동적납미재은무궤항균재료대동일병원균적최저살균농도야불상동,항균솔야불동.
@@@@BACKGROUND: Nano-silver inorganic antimicrobial agent has the characteristics of broad spectrum antimicrobial and antibacterial ability which is one of the hotspots of oral inorganic antibacterial materials research. OBJECTIVE: To study the antibacterial properties and antibacterial mechanism of nano-silver inorganic antimicrobial materials in order to provide reference information for the basic experimental research and the clinical application. METHODS: The antibacterial properties of various oral nano-silver inorganic antimicrobial materials to the common pathogens, such as Streptococcus mutans, Candida albicans and Actinomyces viscosus were analyzed, the antibacterial properties included the minimum bactericidal concentration and antibacterial rate, and the comparative analysis of them was performed. The antibacterial mechanism of nano-silver inorganic antimicrobial materials was researched to clear its advantages and disadvantages. RESULTS AND CONCLUSION: The oral nano-silver inorganic antimicrobial materials had a broad antibacterial spectrum, and had strong antibacterial properties to Streptococcus mutans, Lactobacil us, Actinomyces viscosus, Candida albicans, Porphyromonas gingivalis Aeromonas, Staphylococcus aureus and Escherichia coli. It had the lower minimum bactericidal concentration and the higher antibiotic rate. However, the antibacterial properties of the same nano-silver inorganic antibacterial material for different pathogens were different, showing the different minimum bactericidal concentrations and the different antibacterial rates. On the other hand, different nano-silver inorganic antibacterial materials for the same pathogen had different minimum bactericidal concentrations and different antibacterial rates.