中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2013年
4期
672-677
,共6页
骨关节植入物%骨关节植入物综述%人工关节%肿瘤假体%恶性骨肿瘤%四肢%保肢%大段异体骨%骨移植%微波%灭活%生存率
骨關節植入物%骨關節植入物綜述%人工關節%腫瘤假體%噁性骨腫瘤%四肢%保肢%大段異體骨%骨移植%微波%滅活%生存率
골관절식입물%골관절식입물종술%인공관절%종류가체%악성골종류%사지%보지%대단이체골%골이식%미파%멸활%생존솔
bone and joint implants%review of bone and joint implants%artificial joints%tumor prosthesis%malignant bone tumor%limbs%limb salvage%large segment al ograft bone%bone graft%microwave%inactivation%survival rate
背景:目前保肢手术已经成为四肢恶性骨肿瘤的规范治疗方式,其目的是不但要提高患者的生存率,而且要保存良好的肢体功能.目的:就四肢恶性骨肿瘤人工关节置换及同种异体骨移植等各种保肢方式进行综述.方法:由第一作者应用计算机检索 PubMed 数据库1992年1月至2012年10月及中国期刊网全文数据库1994年1月至2012年12月有关四肢恶性骨肿瘤保肢治疗的文章,英文检索词为“malignant bone tumor,salvage treatment, al ograft bone graft, prosthesis and microwave”,中文检索词为“恶性骨肿瘤,保肢治疗,大段异体骨,肿瘤假体,微波灭活治疗”.排除重复性研究及 Meta 分析,共保留31篇文献进行综述.结果与结论:①对于四肢特别是关节周围的恶性骨肿瘤,大多采用人工关节置换、大段同种异体骨移植以及微波灭活治疗.②大段同种异体骨移植后并发症发生率较高,微波灭活治疗技术有新的进展,进一步的研究仍在进行当中.③瘤段骨灭活再植以及乙醇灭活治疗多适用于基层医院.
揹景:目前保肢手術已經成為四肢噁性骨腫瘤的規範治療方式,其目的是不但要提高患者的生存率,而且要保存良好的肢體功能.目的:就四肢噁性骨腫瘤人工關節置換及同種異體骨移植等各種保肢方式進行綜述.方法:由第一作者應用計算機檢索 PubMed 數據庫1992年1月至2012年10月及中國期刊網全文數據庫1994年1月至2012年12月有關四肢噁性骨腫瘤保肢治療的文章,英文檢索詞為“malignant bone tumor,salvage treatment, al ograft bone graft, prosthesis and microwave”,中文檢索詞為“噁性骨腫瘤,保肢治療,大段異體骨,腫瘤假體,微波滅活治療”.排除重複性研究及 Meta 分析,共保留31篇文獻進行綜述.結果與結論:①對于四肢特彆是關節週圍的噁性骨腫瘤,大多採用人工關節置換、大段同種異體骨移植以及微波滅活治療.②大段同種異體骨移植後併髮癥髮生率較高,微波滅活治療技術有新的進展,進一步的研究仍在進行噹中.③瘤段骨滅活再植以及乙醇滅活治療多適用于基層醫院.
배경:목전보지수술이경성위사지악성골종류적규범치료방식,기목적시불단요제고환자적생존솔,이차요보존량호적지체공능.목적:취사지악성골종류인공관절치환급동충이체골이식등각충보지방식진행종술.방법:유제일작자응용계산궤검색 PubMed 수거고1992년1월지2012년10월급중국기간망전문수거고1994년1월지2012년12월유관사지악성골종류보지치료적문장,영문검색사위“malignant bone tumor,salvage treatment, al ograft bone graft, prosthesis and microwave”,중문검색사위“악성골종류,보지치료,대단이체골,종류가체,미파멸활치료”.배제중복성연구급 Meta 분석,공보류31편문헌진행종술.결과여결론:①대우사지특별시관절주위적악성골종류,대다채용인공관절치환、대단동충이체골이식이급미파멸활치료.②대단동충이체골이식후병발증발생솔교고,미파멸활치료기술유신적진전,진일보적연구잉재진행당중.③류단골멸활재식이급을순멸활치료다괄용우기층의원.
@@@@BACKGROUND: At present, the salvage treatment has become the standard method for the treatment of limbs malignant bone tumor, and the purpose of the surgery is not only to improve the survival rate, but also to save the good limb function. OBJECTIVE: To review several salvage treatments, such as artificial joint replacement and al ograft bone graft for the treatment of limbs malignant bone tumor. METHODS: The PubMed database from January 1992 to October 2012 and China National Knowledge Infrastructure database from January 1994 to December 2012 were searched by the first author for the articles on the treatment of malignant bone tumor with salvage treatment with the key words of “malignant bone tumor, salvage treatment, al ograft bone graft, prosthesis and microwave” in English and Chinese. The repetitive articles and the Meta analysis were eliminated, and final y, a total of 31 articles were included for the review. RESULTS AND CONCLUSION: ①For the malignant bone tumor on limbs, especial y around the joint, the artificial joint replacement, al ograft bone graft and microwave inactivation treatment were the main methods. ②The al ograft bone graft has a high complication incidence, and the microwave inactivation has new progress. The new progress needs further research. ③Tumor segment devitalization and replantation and alcoholic devitalization and replantation are more applicable to the primary hospital.
