中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2013年
5期
797-804
,共8页
左富姐%韩澍%王立明%闵敏%冯小芳%周梅生%李群
左富姐%韓澍%王立明%閔敏%馮小芳%週梅生%李群
좌부저%한주%왕립명%민민%풍소방%주매생%리군
器官移植%肾移植%女性%血液透析%月经%性生活%生育%健康调查表(SF-36)%女性性功能指标量表(FSFI)%调查
器官移植%腎移植%女性%血液透析%月經%性生活%生育%健康調查錶(SF-36)%女性性功能指標量錶(FSFI)%調查
기관이식%신이식%녀성%혈액투석%월경%성생활%생육%건강조사표(SF-36)%녀성성공능지표량표(FSFI)%조사
organ transplantation%renal transplantation%female%hemodialysis%menstruation%sexual life%fertility%the MOS 36-item short-form health survey%female sexual function index scale%survey
背景:理论上讲成功的肾移植可以使生育年龄段女性月经正常化,性生活明显改善,肾移植后可以生育,但国内报道不多.目的:通过自制的“生育年龄段女性肾移植后的月经、性生活、生育状况调查表”并配合生活质量评分表、女性性功能指标量表调查不同生育年龄段女性肾移植前后月经、性生活及移植后生育状况,探讨其影响因素.方法:选择2006年1月至2011年12月在长征医院施行肾移植的生育年龄段患者68例,依据年龄段分为低年组(n=41)和中年组(n=27),以自制的“生育年龄段女性肾移植后的月经、性生活、生育状况调查表”并配合生活质量评分表、女性性功能指标量表进行门诊和电话随访,观察两组患者移植后3年与血液透析期的月经、性生活、生育状况,并分析其影响因素.结果与结论:54例在肾移植后(3.46±1.23)个月月经改善(低年组38例,中年组16例),11例改善不明显(低年组3例,中年组8例),3例较透析前恶化(低年组0例,中年组3例),其中因月经量过多2例行诊刮术,1例行宫腔镜止血术;45例在肾移植后(3.43±1.27)个月性生活改善(低年组34例,中年组11例),11例无明显改善(低年组2例,中年组9例),12例移植后无性生活史(低年组5例,中年组7例).7例肾移植后(30.24±7.86)个月受孕(低年组5例,中年组2例),其中2例生育子女(均为低年组),5例流产.通过患者肾移植后及移植前进行 SF-36量表的调查比较,发现受者在躯体功能、生理职能、躯体疼痛、总体健康、活力领域分值均较移植前明显升高(P <0.05),但在情感职能、心理健康及社会功能领域分值与移植前比较,差异无显著性意义(P >0.05).肾移植后与肾移植前患者 FSFI 量表评分比较,发现肾移植后患者性生活质量各指标中,性欲望、性兴奋、阴道润滑、高潮、满意度分值升高,疼痛分值下降,差异均有显著性意义(P <0.05).结果可见年龄较大受者月经、性生活状况改善也不明显,在严密监护并认真掌控受孕标准的情况下,女性肾移植受者妊娠是可行、安全的.
揹景:理論上講成功的腎移植可以使生育年齡段女性月經正常化,性生活明顯改善,腎移植後可以生育,但國內報道不多.目的:通過自製的“生育年齡段女性腎移植後的月經、性生活、生育狀況調查錶”併配閤生活質量評分錶、女性性功能指標量錶調查不同生育年齡段女性腎移植前後月經、性生活及移植後生育狀況,探討其影響因素.方法:選擇2006年1月至2011年12月在長徵醫院施行腎移植的生育年齡段患者68例,依據年齡段分為低年組(n=41)和中年組(n=27),以自製的“生育年齡段女性腎移植後的月經、性生活、生育狀況調查錶”併配閤生活質量評分錶、女性性功能指標量錶進行門診和電話隨訪,觀察兩組患者移植後3年與血液透析期的月經、性生活、生育狀況,併分析其影響因素.結果與結論:54例在腎移植後(3.46±1.23)箇月月經改善(低年組38例,中年組16例),11例改善不明顯(低年組3例,中年組8例),3例較透析前噁化(低年組0例,中年組3例),其中因月經量過多2例行診颳術,1例行宮腔鏡止血術;45例在腎移植後(3.43±1.27)箇月性生活改善(低年組34例,中年組11例),11例無明顯改善(低年組2例,中年組9例),12例移植後無性生活史(低年組5例,中年組7例).7例腎移植後(30.24±7.86)箇月受孕(低年組5例,中年組2例),其中2例生育子女(均為低年組),5例流產.通過患者腎移植後及移植前進行 SF-36量錶的調查比較,髮現受者在軀體功能、生理職能、軀體疼痛、總體健康、活力領域分值均較移植前明顯升高(P <0.05),但在情感職能、心理健康及社會功能領域分值與移植前比較,差異無顯著性意義(P >0.05).腎移植後與腎移植前患者 FSFI 量錶評分比較,髮現腎移植後患者性生活質量各指標中,性欲望、性興奮、陰道潤滑、高潮、滿意度分值升高,疼痛分值下降,差異均有顯著性意義(P <0.05).結果可見年齡較大受者月經、性生活狀況改善也不明顯,在嚴密鑑護併認真掌控受孕標準的情況下,女性腎移植受者妊娠是可行、安全的.
배경:이론상강성공적신이식가이사생육년령단녀성월경정상화,성생활명현개선,신이식후가이생육,단국내보도불다.목적:통과자제적“생육년령단녀성신이식후적월경、성생활、생육상황조사표”병배합생활질량평분표、녀성성공능지표량표조사불동생육년령단녀성신이식전후월경、성생활급이식후생육상황,탐토기영향인소.방법:선택2006년1월지2011년12월재장정의원시행신이식적생육년령단환자68례,의거년령단분위저년조(n=41)화중년조(n=27),이자제적“생육년령단녀성신이식후적월경、성생활、생육상황조사표”병배합생활질량평분표、녀성성공능지표량표진행문진화전화수방,관찰량조환자이식후3년여혈액투석기적월경、성생활、생육상황,병분석기영향인소.결과여결론:54례재신이식후(3.46±1.23)개월월경개선(저년조38례,중년조16례),11례개선불명현(저년조3례,중년조8례),3례교투석전악화(저년조0례,중년조3례),기중인월경량과다2례행진괄술,1례행궁강경지혈술;45례재신이식후(3.43±1.27)개월성생활개선(저년조34례,중년조11례),11례무명현개선(저년조2례,중년조9례),12례이식후무성생활사(저년조5례,중년조7례).7례신이식후(30.24±7.86)개월수잉(저년조5례,중년조2례),기중2례생육자녀(균위저년조),5례유산.통과환자신이식후급이식전진행 SF-36량표적조사비교,발현수자재구체공능、생리직능、구체동통、총체건강、활력영역분치균교이식전명현승고(P <0.05),단재정감직능、심리건강급사회공능영역분치여이식전비교,차이무현저성의의(P >0.05).신이식후여신이식전환자 FSFI 량표평분비교,발현신이식후환자성생활질량각지표중,성욕망、성흥강、음도윤활、고조、만의도분치승고,동통분치하강,차이균유현저성의의(P <0.05).결과가견년령교대수자월경、성생활상황개선야불명현,재엄밀감호병인진장공수잉표준적정황하,녀성신이식수자임신시가행、안전적.
BACKGROUND: Theoretical y, successful renal transplantation can normalize the menstruation and significantly improve the sexual life of women of childbearing age, and these women can give birth after renal transplantation, but the related domestic reports are rare. OBJECTIVE: To investigate the menstruation, sexual life and birth condition of fertility age women with different ages and to explore the affecting factors through the homemade questionnaire of menstruation, sexual life and birth condition in women of childbearing age after renal transplantation combined with the quality of life scale and female sexual function index scale. METHODS: Sixty-eight women of childbearing age who were treated with renal transplantation in the Changzheng Hospital were selected from January 2006 to December 2011. The patients were divided into young group (n=41) and middle aged group (n=27) on the basis of the age, and then the patients in the two groups received the outpatient and telephone fol ow-up with a homemade questionnaire of menstruation, sexual life and birth condition questionnaire in women of childbearing age after renal transplantation combined with the quality of life scale and female sexual function index scale. The menstruation, sexual life and birth condition of the patients in two groups were observed at 3 years after transplantation and during the blood dialysis stage. RESULTS AND CONCLUSION: For the menstruation of patients, 54 cases (38 cases in the young group and 16 cases in the middle aged group) were improved at (3.46±1.23) months after transplantation; 11 cases (three cases in the young group and eight cases in the middle aged group) were improved not obviously; and three cases (0 case in the young group and three cases in the middle aged group) suffered deterioration before blood dialysis, and due to the excessive menstrual volume, two cases received curettage surgery and one case received hysteroscopy hemostatic surgery. For the sexual life of the patients, 45 cases (34 cases in the young group and 11 cases in the middle aged group) were improved at (3.43±1.27) months after transplantation; 11 cases (two cases in the young group and nine cases in the middle aged group) were improved not obviously; 12 cases (five cases in the young group and seven cases in the middle aged group) without sexual life after transplantation. For the birth condition of the patients, there were seven cases of pregnancy (five cases in the young group and two cases in the middle aged group) at (30.24±7.86) months after transplantation, and two cases in the young group had children successful y and the other five cases of abortion. The MOS 36-item short-form health survey before and after transplantation showed that the physical function, bodily pain, general health and vitality field score were significantly increased compared with those before transplantation (P < 0.05), and there were no significant differences in emotional function, mental health and social function score before and after transplantations (P > 0.05). Comparison of the female sexual function index before and after transplantation showed that the scores on sexual desire, sexual excitement, vaginal lubrication, orgasm and satisfaction were increased after transplantation; while the pain score was decreased, and the differences were statistical y significant (P < 0.05). The results showed that the menstruation and sexual life of the older recipients were not improved obviously, but the pregnancy of the female recipients was feasible and safe under the strict monitoring and control according to the standard seriously conception.
