CAJ | 학술논문

背景:人工肛门为治疗肛门失禁开辟了一条新的思路,然而现有的人工肛门没有感知和反馈功能.患者只能通过习惯而不是肠内容物的实际情况排便.因此人工肛门感知和反馈系统的研制是亟待解决的问题.目的:研制能感知和反馈肠内容物量和压力变化的人工肛门感知系统.方法:通过实验分别向20只新西兰兔近结肠远端10 cm 肠管内注入不同体积的模拟气体、液体、半流体、固体肠内容物,并测量肠管和压力感应套囊的压力变化,分析4种状态肠内容物体积与肠管压力和压力感应套囊压力的关系.结果与结论:实验结果表明,肠管内压力和套囊压力随肠内容物体积的增加而增大,套囊压力与肠内容物体积和肠管压力在一定范围内成正相关.通过实验证实,该生物反馈式人工肛门感知系统能有效的反映肠内容物的多少和肠内压的变化,是解决人工肛门感知和反馈的有效策略,为生物反馈式智能人工肛门的研制打下基础.
배경:인공항문위치료항문실금개벽료일조신적사로,연이현유적인공항문몰유감지화반궤공능.환자지능통과습관이불시장내용물적실제정황배편.인차인공항문감지화반궤계통적연제시극대해결적문제.목적:연제능감지화반궤장내용물량화압력변화적인공항문감지계통.방법:통과실험분별향20지신서란토근결장원단10 cm 장관내주입불동체적적모의기체、액체、반류체、고체장내용물,병측량장관화압력감응투낭적압력변화,분석4충상태장내용물체적여장관압력화압력감응투낭압력적관계.결과여결론:실험결과표명,장관내압력화투낭압력수장내용물체적적증가이증대,투낭압력여장내용물체적화장관압력재일정범위내성정상관.통과실험증실,해생물반궤식인공항문감지계통능유효적반영장내용물적다소화장내압적변화,시해결인공항문감지화반궤적유효책략,위생물반궤식지능인공항문적연제타하기출.
@@@@BACKGROUND: Artificial anal sphincter is a new way to treat fecal incontinence. However, present artificial anal sphincter lacks of awareness and feedback function, and patients can control their defecation mainly through their habits rather than the existence of the intestinal contents. Research into an awareness and feedback system is the primary issue in the development of artificial anal sphincter. OBJECTIVE: To develop a bio-feedback artificial anal sphincter perception system which could perceive and feedback the change in intestinal pressure and the volume of intestinal contents. METHODS: Twenty healthy New Zealand rabbits were used to test its feasibility, and the experiments were performed on the distal part of proximal colon of the rabbits. The pressure of intestinal canal and pressure sensing cuff were measured after injecting four simulated intestinal contents, including gas, liquid, semi-fluid and solid into the intestinal canal respectively. The relationship between the volume of the four states of intestinal contents and the intestinal canal pressure and the cuff pressure was analyzed. RESULTS AND CONCLUSION: The results of the experiment showed that the pressure of intestinal canal and pressure sensing cuff was increased with the increasing of the volume of intestinal contents, and the pressure and the volume was positively correlated within a certain range. According to the experiment, the bio-feedback artificial anal sphincter perception system could effectively reflect the change of intestinal pressure and the volume of intestinal contents, and may be an effective strategy to address the awareness and feedback problem of artificial anal sphincter, thereby laying the basis for the research of intel igent bio-feedback artificial anal sphincter.