中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2013年
7期
1180-1184
,共5页
王尚城%王冬梅%汪方%王秋根%王春慧%陈善广
王尚城%王鼕梅%汪方%王鞦根%王春慧%陳善廣
왕상성%왕동매%왕방%왕추근%왕춘혜%진선엄
组织构建%组织构建与生物力学%皮质骨%松质骨%力学性能%测试%生物力学%国家自然科学基金
組織構建%組織構建與生物力學%皮質骨%鬆質骨%力學性能%測試%生物力學%國傢自然科學基金
조직구건%조직구건여생물역학%피질골%송질골%역학성능%측시%생물역학%국가자연과학기금
tissue construction%tissue construction and biomechanics%cortical bone%cancel ous bone%mechanical property%testing%biomechanics%the National Natural Science Foundation of China
背景:人体骨组织材料力学性能参数是进行骨骼内部应力计算分析、断裂损伤分析、应力骨改建研究等的基础数据,也是深入开展人体骨骼生物力学行为特性研究的必要已知条件之一,但目前国际上还没有统一的骨组织力学性能测试的试验标准.目的:探讨骨组织拉压力学性能测试的试样制备、试样约束和夹持、试验数据处理和试验误差等问题的研究进展.方法:在骨组织拉伸压缩试验无具体标准可循的环境下,对已验证的试验方法和途径进行介绍.总结并强调了骨组织拉压试验中的各项误差及其减少;以减少系统误差为目的,介绍了规范的骨组织宏观拉压测试方法.结果与结论:通过拉伸压缩试验可获得骨组织的弹性模量、泊松比、拉伸强度和压缩强度等重要力学性能参数,测试关键环节涉及标准试样设计和加工、试件夹持、试验数据处理和力学参数的计算,各环节均需参照最新研究以减少试验误差.
揹景:人體骨組織材料力學性能參數是進行骨骼內部應力計算分析、斷裂損傷分析、應力骨改建研究等的基礎數據,也是深入開展人體骨骼生物力學行為特性研究的必要已知條件之一,但目前國際上還沒有統一的骨組織力學性能測試的試驗標準.目的:探討骨組織拉壓力學性能測試的試樣製備、試樣約束和夾持、試驗數據處理和試驗誤差等問題的研究進展.方法:在骨組織拉伸壓縮試驗無具體標準可循的環境下,對已驗證的試驗方法和途徑進行介紹.總結併彊調瞭骨組織拉壓試驗中的各項誤差及其減少;以減少繫統誤差為目的,介紹瞭規範的骨組織宏觀拉壓測試方法.結果與結論:通過拉伸壓縮試驗可穫得骨組織的彈性模量、泊鬆比、拉伸彊度和壓縮彊度等重要力學性能參數,測試關鍵環節涉及標準試樣設計和加工、試件夾持、試驗數據處理和力學參數的計算,各環節均需參照最新研究以減少試驗誤差.
배경:인체골조직재료역학성능삼수시진행골격내부응력계산분석、단렬손상분석、응력골개건연구등적기출수거,야시심입개전인체골격생물역학행위특성연구적필요이지조건지일,단목전국제상환몰유통일적골조직역학성능측시적시험표준.목적:탐토골조직랍압역학성능측시적시양제비、시양약속화협지、시험수거처리화시험오차등문제적연구진전.방법:재골조직랍신압축시험무구체표준가순적배경하,대이험증적시험방법화도경진행개소.총결병강조료골조직랍압시험중적각항오차급기감소;이감소계통오차위목적,개소료규범적골조직굉관랍압측시방법.결과여결론:통과랍신압축시험가획득골조직적탄성모량、박송비、랍신강도화압축강도등중요역학성능삼수,측시관건배절섭급표준시양설계화가공、시건협지、시험수거처리화역학삼수적계산,각배절균수삼조최신연구이감소시험오차.
@@@@BACKGROUND: The mechanical parameters of human bone tissue materials are not only the fundamental data for the stress calculation, fracture damage analysis and stress-related bone remodeling, but also one of the main indispensable factors for the further investigation of the characteristics of biomechanical behavior of human bone. However, no international standards for the bone mechanical property tests have been reported. OBJECTIVE: To summarize the research progress on the topics of specimen preparation, specimen constraints and fixation, test data processing and experiment error of tension-compression testing. METHODS: Under the environment of no specific standard for the tensile and compression testing of bone tissue to fol ow, the verified test methods and ways were introduced. The error and its decrease during the tension-compression testing were concluded and emphasized; the standardized bone tissue macro tension and compression test method was also introduced with the purpose of reducing the systematic errors. RESULTS AND CONCLUSION: By performing the tension-compression testing, key parameters such as elastic modulus, Poisson’s ratio, tensile strength and compress strength of the bone tissue could be acquired. Important testing procedures involving designing and machining of standard specimen, specimen gripping, data processing and mechanical parameter calculation were tested. During each procedure, the systematic errors need to be reduced according to the latest researches.