CAJ | 학술논문

生物材料%材料生物相容性%生物材料基础实验%明胶海绵粉末%髂内动脉%栓塞%血管造影%骶骨肿瘤%省级基金%生物材料图片文章生物材料%材料生物相容性%生物材料基礎實驗%明膠海綿粉末%髂內動脈%栓塞%血管造影%骶骨腫瘤%省級基金%生物材料圖片文章
생물재료%재료생물상용성%생물재료기출실험%명효해면분말%가내동맥%전새%혈관조영%저골종류%성급기금%생물재료도편문장
biomaterials%material biocompatibility%basic experiments of biomaterials%gelfoam powder%internal iliac artery%embolism%angiography%sacral tumor%provincial grants-supported paper%biomaterial photographs-containing paper

背景:明胶海绵已成为骶骨肿瘤术前栓塞的首选材料,但针对小颗粒明胶海绵对栓塞效果及栓塞后并发症的影响未见明确报道.目的:观察小颗粒明胶海绵栓塞犬双侧髂内动脉后手术出血量变化和并发症情况.方法:用直径为50-150μm 明胶海绵粉末对15只犬行双侧髂内及骶正中动脉栓塞,分别于栓塞后1,2,3 d 模拟骶骨肿瘤手术测量出血量变化;病理观察栓塞区膀胱、直肠、臀部肌及坐骨神经变化.结果与结论:栓塞后第3天出血量高于第1,2天(P <0.05),栓塞后第1天与第2天出血量差异无显著性意义(P >0.05).在运用直径为50-150μm 明胶海绵粉末栓塞犬双侧髂内及骶正中动脉时,最小动脉是50μm 的微动脉,但主要集中在100-200μm 小动脉,数字减影血管造影下显示栓塞双侧髂内及骶正中动脉近端血管级别为其一级分支,此时犬盆腔脏器组织无明显变化.
배경:명효해면이성위저골종류술전전새적수선재료,단침대소과립명효해면대전새효과급전새후병발증적영향미견명학보도.목적:관찰소과립명효해면전새견쌍측가내동맥후수술출혈량변화화병발증정황.방법:용직경위50-150μm 명효해면분말대15지견행쌍측가내급저정중동맥전새,분별우전새후1,2,3 d 모의저골종류수술측량출혈량변화;병리관찰전새구방광、직장、둔부기급좌골신경변화.결과여결론:전새후제3천출혈량고우제1,2천(P <0.05),전새후제1천여제2천출혈량차이무현저성의의(P >0.05).재운용직경위50-150μm 명효해면분말전새견쌍측가내급저정중동맥시,최소동맥시50μm 적미동맥,단주요집중재100-200μm 소동맥,수자감영혈관조영하현시전새쌍측가내급저정중동맥근단혈관급별위기일급분지,차시견분강장기조직무명현변화.
@@@@BACKGROUND: Gelfoam has become the preferred embolization agent for preoperative embolism in the operation of sacral tumor, but the contribution of smal gelfoam to embolization effectiveness and postoperative complications has not been definitely reported. OBJECTIVE: To observe the changes in intraoperative bleeding and complications fol owing embolization of dog’s bilateral internal iliac arteries with gelfoam powder. METHODS: The bilateral internal iliac and median sacral arteries of fifteen dogs were embolized using gelfoam powder with a diameter of 50-150 μm. Then, the operation of sacral tumor was imitated to measure intraoperative bleeding at 1, 2, and 3 days after embolization, observing pathological alteration of pelvic organs. RESULTS AND CONCLUSION: The mean intraoperative bleeding was higher at 3 days than at 1 and 2 days (P < 0.0.5), but it was no difference at 1 and 2 days (P > 0.05). When gelfoam power with a diameter of 50-150 μm was employed to embolize the bilateral internal iliac and median sacral arteries, the smal est embolized artery was arteriole whose diameter was about 50 μm, but embolized arteries were mainly arterioles with a diameter of 100-200 μm. The first-class branches of embolized bilateral internal iliac and median sacral arteries were reserved which were displayed on the digital subtraction angiography. In addition, pelvic organs had no obvious pathological alteration.