CAJ | 학술논문

传染性支气管炎(IB)是由冠状病毒科传染性支气管炎病毒(IBV)引起的高度接触性传染病.该病在世界各地均有发生,给全球养禽业造成巨大的经济损失.IBV感染宿主细胞的第一步是病毒与细胞表面的受体结合,介导病毒颗粒进入细胞内.IBV病毒受体的研究对于揭示IBV的致病和免疫机理具有重要价值.文中就近年来发现的氨基肽酶N、硫酸乙酰肝素和唾液酸受体作综述.
전염성지기관염(IB)시유관상병독과전염성지기관염병독(IBV)인기적고도접촉성전염병.해병재세계각지균유발생,급전구양금업조성거대적경제손실.IBV감염숙주세포적제일보시병독여세포표면적수체결합,개도병독과립진입세포내.IBV병독수체적연구대우게시IBV적치병화면역궤리구유중요개치.문중취근년래발현적안기태매N、류산을선간소화타액산수체작종술.
@@@@Avian infectious bronchitis is a high contagious disease,resulted in huge economic loss and threaten poultry husbandry worldwide.The causative agent,Avian Infectious bronchitis virus (IBV),belonged to Coronaviridae of Nidovirales.The attachment of IBV to the receptor on the surface of host cells is the first stage of virus infection,through which virus can entry the cell.Study on the receptors of IBV is significant in understanding the pathogenesis and immunologic mechanism of IBV.This article mainly described the recent advances on the receptors of IBV,including aminopeptidase N,heparan sulfate and sialic acid.