CAJ | 학술논문

在经过碱热处理的纯钛表面采用溶胶-凝胶法和提拉涂覆法制备含氟羟基磷灰石(FHA)-锶取代羟基磷灰石(SrHA)双相生物陶瓷涂层.采用X射线衍射检测涂层的相组成,采用扫描电镜观察涂层的形貌,采用划痕法测定涂层与基体的结合力.结果表明:所制备的涂层是均匀和致密的FHA-SrHA双相涂层;与单相FHA和SrHA涂层相比,FHA-SrHA双相涂层与钛基体的结合力明显优于SrHA涂层,略低于FHA涂层;TRIS溶液中的溶解性实验结果显示3种涂层均发生溶解和钙磷酸盐的重沉积过程,表现出良好的生物活性,但FHA-SrHA双相涂层的溶解速率远远低于单相FHA及SrHA涂层,这表明可以通过双相涂层设计来提高生物陶瓷涂层材料的植入寿命和稳定性.
재경과감열처리적순태표면채용용효-응효법화제랍도복법제비함불간기린회석(FHA)-송취대간기린회석(SrHA)쌍상생물도자도층.채용X사선연사검측도층적상조성,채용소묘전경관찰도층적형모,채용화흔법측정도층여기체적결합력.결과표명:소제비적도층시균균화치밀적FHA-SrHA쌍상도층;여단상FHA화SrHA도층상비,FHA-SrHA쌍상도층여태기체적결합력명현우우SrHA도층,략저우FHA도층;TRIS용액중적용해성실험결과현시3충도층균발생용해화개린산염적중침적과정,표현출량호적생물활성,단FHA-SrHA쌍상도층적용해속솔원원저우단상FHA급SrHA도층,저표명가이통과쌍상도층설계래제고생물도자도층재료적식입수명화은정성.
Colloidal sol-gel derived Fluor-hydroxyapatite (FHA) and strontium-substituted hydroxyapatite (SrHA) biphasic coating (FHA-SrHA) was prepared on a titanium substrate by alkali-heat-treatment. The phase composition of the coating was analyzed by X-ray diffraction, surface morphology and structure of the coating were observed by scanning electron microscope, the adhesion strength of the coating was analyzed by scratching test. The results show that the obtained FHA-SrHA coating is uniform, dense and biphasic. The biphasic film exhibits superior adherence to the titanium substrate in comparison to the single SrHA coating, but inferior adherence to the single FHA coating. Solubility experiment in TRIS solution shows that FHA, SrHA and FHA-SrHA coatings proceeded a process of dissolving and re-precipitating calcium phosphate. However, the dissolution rate of the biphasic FHA-SrHA coating is much lower than that of FHA and SrHA coating, which suggests the possibility of extending the planting period by designing biphasic coating of FHA-SrHA.