CAJ | 학술논문

目的通过测定急性心肌梗死(AMI)心肌损伤标志物脂肪酸结合蛋白(H-FABP)、缺血修饰蛋白(IMA),比较其对AMI早期诊断的价值.方法选取AMI患者51例分别于胸痛发作2 h、3 h、6 h、9 h、24 h采血测定H-FABP、IMA等指标,采用中华医学会心血管分会2001年12月制订的AMI诊断标准作为金标准,计算几种指标在各时间点的敏感性并相互比较.结果在AMI胸痛发作2 h,H-FABP、IMA敏感性分别为62.7%、76.5%;胸痛发作3 h,H-FABP、IMA敏感性分别为82.4%、86.3%;胸痛发作6 h,H-FABP、IMA敏感性分别为84.3%、80.4%;胸痛发作9 h,H-FABP、IMA敏感性分别为64.7%、54.9%;胸痛发作24 h,H-FABP、IMA敏感性分别为37.3%、23.5%.结论 AMI早期H-FABP及IMA 均具有较高的敏感性.
목적통과측정급성심기경사(AMI)심기손상표지물지방산결합단백(H-FABP)、결혈수식단백(IMA),비교기대AMI조기진단적개치.방법선취AMI환자51례분별우흉통발작2 h、3 h、6 h、9 h、24 h채혈측정H-FABP、IMA등지표,채용중화의학회심혈관분회2001년12월제정적AMI진단표준작위금표준,계산궤충지표재각시간점적민감성병상호비교.결과재AMI흉통발작2 h,H-FABP、IMA민감성분별위62.7%、76.5%;흉통발작3 h,H-FABP、IMA민감성분별위82.4%、86.3%;흉통발작6 h,H-FABP、IMA민감성분별위84.3%、80.4%;흉통발작9 h,H-FABP、IMA민감성분별위64.7%、54.9%;흉통발작24 h,H-FABP、IMA민감성분별위37.3%、23.5%.결론 AMI조기H-FABP급IMA 균구유교고적민감성.
@@@@Objectiv To evaluate the sensitivity of heart-type fatty acid-binding protein (H-FABP) and ischaemia modified albumin (IMA) in acute myocardial infarction (AMI) and compare theirs diagnostic efficacy in early stage AMI. Methods The creteria pulished by Chinese society of cardiology at December, 2001 was taken as the golden standard. H-FABP and IMA were measured in AMI patients at 2 h, 3 h, 6 h, 9 h, 24 h after the onset of chest pain, and the efficacy of these index were evaluated. Results At 2 h after chest pain, the sensitivity rate of H-FABP was 62.7%, the sensitivity of IMA was 76.5%. At 3 h after chest pain, the sensitivity rate of H-FABP was 82.4%, the sensitivity of IMA was 86.3%. At 6 h after chest pain, the sensitivity rate of H-FABP was 84.3%, the sensitivity of IMA was 80.4%. At 9 h after chest pain, the sensitivity rate of H-FABP was 64.7%, the sensitivity of IMA was 54.9%. At 24 h after chest pain, the sensitivity rate of H-FABP was 37.3%, the sensitivity of IMA was 23.5%. conclusion The sensitivity of H-FABP and IMA is high.