CAJ | 학술논문

目的:观察灯盏花素对链脲佐菌素诱导糖尿病大鼠的膀胱逼尿肌的影响.方法:雌性SD大鼠分为正常对照组(C组)、糖尿病组(D组)、糖尿病灯盏花素治疗组(DD组).以高糖高脂饮食及小剂量连脲佐菌素(30mg/kg)制备2型糖尿病大鼠模型.16周后光镜下观察膀胱逼尿肌在常规HE染色和苦味酸酸性品红(V-G)染色的改变.结果:糖尿病组大鼠与正常对照组差异明显,治疗组较糖尿病组明显下降.结论:在链脲佐菌素诱导糖尿病大鼠,灯盏花素具有保护膀胱逼尿肌功能.
목적:관찰등잔화소대련뇨좌균소유도당뇨병대서적방광핍뇨기적영향.방법:자성SD대서분위정상대조조(C조)、당뇨병조(D조)、당뇨병등잔화소치료조(DD조).이고당고지음식급소제량련뇨좌균소(30mg/kg)제비2형당뇨병대서모형.16주후광경하관찰방광핍뇨기재상규HE염색화고미산산성품홍(V-G)염색적개변.결과:당뇨병조대서여정상대조조차이명현,치료조교당뇨병조명현하강.결론:재련뇨좌균소유도당뇨병대서,등잔화소구유보호방광핍뇨기공능.
Objective: To observe the effect of breviscapine on streptozotocin induced diabetic rats bladder detrusor. Methods:Female SD rats were divided into normal control group ( group C), diabetic group ( group D), diabetic breviscapine treatment group (group DD ). By high-fat diet and low dose with streptozotocin ( 30mg/kg ) preparation of rat model of type 2 diabetes. 16 Zhou Houguang observation of bladder detrusor in routine HE staining and bitter acid fuchsin staining ( V-G) changes. Results:Diabetic rats and normal control groups differed significantly, the treatment group was significantly decreased compared with the diabetic group. Conclusion: In the diabetic rats induced by STZ in, breviscapine could protect the detrusor function.