CAJ | 학술논문

目的:探讨阿法骨化醇治疗和预防老年性骨质疏松的疗效及预防措施.方法:200例老年原发性骨质疏松症患者随机分成两组,治疗组和对照组各100例.对照组患者每天口服钙剂,治疗组在此基础上加服阿法骨化醇.结果:两组患者治疗前骨密度比较差异无统计学意义(P>0.05).治疗后两组指标都有明显升高,但治疗组骨密度较对照组增加更明显,有统计学意义(P<0.05).治疗组疼痛改善率78%,对照组为35%,治疗组明显好于对照组(P<0.05).结论:阿法骨化醇治疗老年性骨质疏松症能够有效提高骨密度,缓解疼痛.
목적:탐토아법골화순치료화예방노년성골질소송적료효급예방조시.방법:200례노년원발성골질소송증환자수궤분성량조,치료조화대조조각100례.대조조환자매천구복개제,치료조재차기출상가복아법골화순.결과:량조환자치료전골밀도비교차이무통계학의의(P>0.05).치료후량조지표도유명현승고,단치료조골밀도교대조조증가경명현,유통계학의의(P<0.05).치료조동통개선솔78%,대조조위35%,치료조명현호우대조조(P<0.05).결론:아법골화순치료노년성골질소송증능구유효제고골밀도,완해동통.
@@@@Objective:To explore the therapeutic efficacy of alfacalcidol on senile osteoporosis and to discuss its preventive measures.Methods:Two hundred elderly patients with primary osteoporosis were divided into two groups (each n=100).Patients in the control group were treated with basic daily oral calcium while alfacalcidol therapy was additinally given in the treatment group besides the basic treatment.Results:Before the treatment, no statistically significant difference was found between the two groups (P>0.05).After the treatment, the indicators of patients in the two groups were significantly increased, however bone mineral density (BMD) at the femoral neck and L 2-4 were significantly higher in the treatment group than in the control group (P<0.05).The total response rate of pain improvement was 78.0%in the treatment group and 35.0%in the control group, and the treatment group was superior to the control group (P<0.05). Conclusion:Alfacalcidol for the treatment of senile osteoporosis can effectively improve bone mineral density and relieve the pain.