CAJ | 학술논문

目的:探讨皮贴雌激素在不孕症治疗中的应用.方法:入选诊断为不孕症需用外源性雌激素的患者,排除外输卵管等其他因素所致不孕症及不适合用药的疾病.应用皮贴雌激素进行治疗,观察用药前后宫颈黏液Insler评分及子宫内膜厚度的变化,并对应用CC/HMG患者加快卵泡发育的影响,用阴超监测子宫内膜厚度和卵泡大小,测定体内雌激素水平的变化,以及受孕情况.结果:应用皮贴雌激素3~4 h即可达到有效的血浆浓度并保持在这个水平达7 d之久,改善宫颈黏液性状、量增加变稀薄,拉丝度增加,子宫内膜增厚,促进卵泡发育成熟,妊娠率增加.结论:皮贴雌激素可改善宫颈黏液的性状,促进子宫内膜的生长,促进卵泡的发育并增加妊娠率,提示其可应用于生殖医学尤其是不孕症的治疗中.
목적:탐토피첩자격소재불잉증치료중적응용.방법:입선진단위불잉증수용외원성자격소적환자,배제외수란관등기타인소소치불잉증급불괄합용약적질병.응용피첩자격소진행치료,관찰용약전후궁경점액Insler평분급자궁내막후도적변화,병대응용CC/HMG환자가쾌란포발육적영향,용음초감측자궁내막후도화란포대소,측정체내자격소수평적변화,이급수잉정황.결과:응용피첩자격소3~4 h즉가체도유효적혈장농도병보지재저개수평체7 d지구,개선궁경점액성상、량증가변희박,랍사도증가,자궁내막증후,촉진란포발육성숙,임신솔증가.결론:피첩자격소가개선궁경점액적성상,촉진자궁내막적생장,촉진란포적발육병증가임신솔,제시기가응용우생식의학우기시불잉증적치료중.
@@@@Objective:to investigate the improvement and adjustment of conception factor of barrenness patients who have applied Fem 7 estradiol patch, and to promote the clinical observation of conception effect. Methods:Eight hundred and ninety eight cases who are diagnosed as barrenness and need exogenous estrogen are selected. The patients, for whom other incompetent diseases are excluded, accept therapy as request. The changes of cervical mucus (CM), endometria and the effect of HMG on follicular development before and after medication are observed. The endometria thickness, egg follicle size, the changes of estrogen level and ultimate conception are detected. Results:The effective plasma concentration can be reached within 3~4 hours after application of Fem 7 patch and retained for 7days. Conclusion:The application of Fem 7 patch in the barrenness of generation medicine can improve the quality of cervical mucus, promote the growth of endometria, accelerate follicular development and increase pregnancy rate .