CAJ | 학술논문

目的探讨 H 型高血压与老年脑梗塞的相关性.方法选取潍坊市人民医院2011年10月~2012年10月收治的121例老年(均年龄≥60岁)原发性高血压(EH)高血压合并脑梗塞患者为研究对象,其中按照高血压同型半胱氨酸(Hcy)水平是否≥10μmol/L,将其分为 H 型高血压组(H 型组)59例和单纯性高血压组(单纯组)61例,根据患者颅脑 CT 或 MRI 是否有梗塞灶,分为脑梗塞组和非脑梗组.并测三酰甘油(TG)、胆固醇(TC)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)等生化指标及收集年龄、性别、吸烟史、饮酒史等流行病学资料.结果脑梗塞组患者的 Hcy 水平显著高于非脑梗组(P <0.01);且 H 型组较单纯组脑梗塞患者病例数高(P <0.05);经 Person 相关性分析示:r =0.25,P <0.01,说明 H 型高血压与老年脑梗塞的发病有一定的相关性,可能是老年脑梗塞发生的危险因子.结论 H 型高血压与老年脑梗塞的的高发生率有关,降低 Hcy 水平可能使我国脑梗死的高发生率得到改善.
목적탐토 H 형고혈압여노년뇌경새적상관성.방법선취유방시인민의원2011년10월~2012년10월수치적121례노년(균년령≥60세)원발성고혈압(EH)고혈압합병뇌경새환자위연구대상,기중안조고혈압동형반광안산(Hcy)수평시부≥10μmol/L,장기분위 H 형고혈압조(H 형조)59례화단순성고혈압조(단순조)61례,근거환자로뇌 CT 혹 MRI 시부유경새조,분위뇌경새조화비뇌경조.병측삼선감유(TG)、담고순(TC)、저밀도지단백(LDL-C)、고밀도지단백(HDL-C)등생화지표급수집년령、성별、흡연사、음주사등류행병학자료.결과뇌경새조환자적 Hcy 수평현저고우비뇌경조(P <0.01);차 H 형조교단순조뇌경새환자병례수고(P <0.05);경 Person 상관성분석시:r =0.25,P <0.01,설명 H 형고혈압여노년뇌경새적발병유일정적상관성,가능시노년뇌경새발생적위험인자.결론 H 형고혈압여노년뇌경새적적고발생솔유관,강저 Hcy 수평가능사아국뇌경사적고발생솔득도개선.
@@@@Objective To investigate the correlation of H type hypertension and senile cerebral infarction .Methods One hun-dred and twenty-one elderly patients(age≥60 years) were chosen in weifang people 's hospital from October 2011 to October 2012,with es-sential hypertension(EH) and with cerebra infarction as the research objects .According to the hypertension homocysteine ( Hcy) levels (whether was higher than 10μmol /L),they were classified into H-type hypertension group (H group,59 cases) and simple hypertension group(simple group,61 cases),according to the patient's brain CT or MRI infarct,they were divided into the cerebral infarction group and non-cerebral infarction group.And triacyl glycerol(TG),cholesterol(TC),low-density lipoprotein (LDL-C),high density lipoprotein (HDL-C) and other biochemical indicators were measured and age ,sex,smoking history,history of alcohol consumption and other epidemiological data were collected.Results Hcy level of cerebral infarction group was significantly higher than that of non -cerebral infarction group(P <0. 01);Compared to simple group,the number of cerebral infarction cases in H -type group was higher(P <0.05);correlation analysis indica-ted:(r =0.25,P <0.01),H-type hypertension had correlation with the incidence of senile cerebral infarction ,which might be a risk factor. Conclusion The high incidence of H-type hypertension is related to senile cerebral infarction ,and the incidence of cerebral infarction may be controlled by decrease the level of Hcy .