CAJ | 학술논문

目的探讨椎基底动脉延长扩张症(VBD)患者动态 CT 灌注成像方法的应用价值.方法2011年2月~2012年3月经临床及影像学检查确诊为 VBD 的患者13例为观察组,同期22例临床和 CT 均提示无颅脑疾病者为正常对照组,记录年龄,进行动态CT 灌注成像,在双侧小脑半球、小脑脚及桥脑白质区对称各选取3个感兴趣区,分别测量各组脑血流量(CBF)、脑血容量(CBV)、平均通过时间(MTT)和达峰时间(TTP),以及观察组基底动脉的直径.结果两组桥脑、小脑脚和小脑白质的 TTP 相比具有显著性差异(P<0.05),而 CBF、CBV 及 MTT 无显著性差异(P>0.05).观察组年龄和基底动脉直径与桥脑、小脑脚和小脑白质的 CBF、CBV、MTT 及 TTP 相比无显著性相关(P>0.05).结论 CT 灌注成像可以显示 VBD 后循环灌注的特异性,作为其血流动力学方面的辅助诊断.
목적탐토추기저동맥연장확장증(VBD)환자동태 CT 관주성상방법적응용개치.방법2011년2월~2012년3월경림상급영상학검사학진위 VBD 적환자13례위관찰조,동기22례림상화 CT 균제시무로뇌질병자위정상대조조,기록년령,진행동태CT 관주성상,재쌍측소뇌반구、소뇌각급교뇌백질구대칭각선취3개감흥취구,분별측량각조뇌혈류량(CBF)、뇌혈용량(CBV)、평균통과시간(MTT)화체봉시간(TTP),이급관찰조기저동맥적직경.결과량조교뇌、소뇌각화소뇌백질적 TTP 상비구유현저성차이(P<0.05),이 CBF、CBV 급 MTT 무현저성차이(P>0.05).관찰조년령화기저동맥직경여교뇌、소뇌각화소뇌백질적 CBF、CBV、MTT 급 TTP 상비무현저성상관(P>0.05).결론 CT 관주성상가이현시 VBD 후순배관주적특이성,작위기혈류동역학방면적보조진단.
@@@@Objective To evaluate the features of CT perfusion for vertebrobasilar dolichoectasia (VBD). Methods The image data of 13 cases with VBD as observation group and 22 cases of normal controls were retrospectively analyzed from February 2011 to March 2012. 3 regions of interest (ROI) in white matter of cerebellum, cerebellar peduncle and pons were drown symmetry to measure the parameters in-cluding cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT) and time to peak (TTP). The diameter of basilar artery and the age of the observation group were also measured. Results There was significant difference between 2 groups in TTP in all ROI (P<0.05), and no significant difference in CBF, CBV and MTT in all ROIs (P>0.05). The age, the diameter of basilar artery did not cor-related with perfusion parameters (P>0.05) in the observation group. Conclusion CT perfusion imaging can demonstrate some features of posterior circulation as auxiliary diagnosis of VBD.