CAJ | 학술논문

目的:探讨胸水中INF-γ、ADA、CEA、CA125四项指标联合检测对于鉴别良恶性胸腔积液的意义和诊断价值.方法:收集2011年1月-2012年12月在笔者所在医院治疗的136例胸腔积液患者,经病理诊断分恶性组(n=75)和良性组(n=61),检测患者的胸水中CEA、CA125和INF-γ、ADA活性,并对检测结果进行比对分析.结果:恶性组肿瘤标志物CEA、CA125水平明显高于良性组, INF-γ、ADA表达水平明显低于良性组,差异具有统计学意义(P<0.05).联合检测可显著提高诊断敏感性(93.3%).结论:联合检测胸水中INF-γ、ADA、CEA、CA125四项指标,对鉴别良恶性胸腔积液有重要诊断意义和临床价值.
목적:탐토흉수중INF-γ、ADA、CEA、CA125사항지표연합검측대우감별량악성흉강적액적의의화진단개치.방법:수집2011년1월-2012년12월재필자소재의원치료적136례흉강적액환자,경병리진단분악성조(n=75)화량성조(n=61),검측환자적흉수중CEA、CA125화INF-γ、ADA활성,병대검측결과진행비대분석.결과:악성조종류표지물CEA、CA125수평명현고우량성조, INF-γ、ADA표체수평명현저우량성조,차이구유통계학의의(P<0.05).연합검측가현저제고진단민감성(93.3%).결론:연합검측흉수중INF-γ、ADA、CEA、CA125사항지표,대감별량악성흉강적액유중요진단의의화림상개치.
Objective:To investigate the INF-γ、ADA、CEA、CA125 indicators of significance and diagnostic value for differentiating benign and malignant pleural effusion.Method:Collected 136 cases of patients with pleural effusion treated in our hospital,and divided into malignant group (n=75)and benign group(n=61).Compared results of INF-γ,ADA,CEA CA125 between two groups.Result:Malignancy tumor markers CEA and CA125 level of malignant group were significantly higher than those in benign group,while INF-γ,ADA expression level were significantly lower than that in benign group,with statistically significant difference(P<0.05).Joint detection can significantly improved the diagnostic sensitivity(93.3%). Conclusion:The joint detection of INF-γ,ADA,CEA,CA125 have important diagnostic significance and clinical value in differentiating benign and malignant pleural effusion.