CAJ | 학술논문

目的分析胰岛素抵抗(IR)在老老年高血压与青年高血压患者中的不同特点.方法连续入选老老年高血压患者98例,同期入选98例青年高血压患者.测定空腹血糖、空腹血浆胰岛素等.用自我平衡模型分析法(HOMA)指数(IRI)评价胰岛素抵抗.治疗并随访6个月.进行相关数据统计分析.结果老老年高血压组患者的血脂水平与体质指数显著低于青年高血压组(P<0.05),而空腹血糖、空腹血浆胰岛素、IRI以及IRI≥2.69比例两组间无显著差异.有效治疗后,青年高血压组的IRI下降值明显高于老老年高血压组(P<0.05).结论在非糖尿病人群,老老年高血压患者的IR程度与青年高血压患者无明显差异,但青年高血压患者的IR更易改善.
목적분석이도소저항(IR)재로노년고혈압여청년고혈압환자중적불동특점.방법련속입선로노년고혈압환자98례,동기입선98례청년고혈압환자.측정공복혈당、공복혈장이도소등.용자아평형모형분석법(HOMA)지수(IRI)평개이도소저항.치료병수방6개월.진행상관수거통계분석.결과로노년고혈압조환자적혈지수평여체질지수현저저우청년고혈압조(P<0.05),이공복혈당、공복혈장이도소、IRI이급IRI≥2.69비례량조간무현저차이.유효치료후,청년고혈압조적IRI하강치명현고우로노년고혈압조(P<0.05).결론재비당뇨병인군,로노년고혈압환자적IR정도여청년고혈압환자무명현차이,단청년고혈압환자적IR경역개선.
Objective To discuss the difference of insulin resistance(IR) between very elderly and young patients with hypertension.Methods 98 consecutive very elderly patients with hypertension were enrolled in this study,and 98 young patients with hypertension as the control.The metabolic parameters and homeostasis model assessmem for IR(IRI) were measured.The patients were treated and followed up for 6 months.Results Fasting blood glucose,plasma insulin level,and IRI were similar between the two groups.The triglyceride,total cholesterol,low density lipoprotein,body mass index were significantly lower in very elderly patients with hypertension.IRI in young hypertension was decreased faster after effective treatment.Conclusion The degree of IR was similar between very elderly hypertension and young hypertension without diabetes.But IR in young hypertension was ameliorated faster after effective treatment.