CAJ | 학술논문

目的:探究赖脯胰岛素50对初诊2型糖尿病血糖和胰岛β细胞功能的影响.方法:选取笔者所在医院内分泌科的住院初诊为2型糖尿病患者共122例,采用电脑的随机的方法,将受试对象随机分为常规组和赖脯组各61例,常规组用优泌林混合型、赖脯组用赖脯胰岛素50进行降糖治疗,测量两组患者治疗前后各项血糖和C肽相关指标的变化情况.结果:两组患者血糖都有良好的控制,相互没有差异;但常规组患者治疗前后C肽水平没有明显变化;赖脯组治疗前后C肽水平有明显变化,并且较常规组差异明显.结论:赖脯胰岛素50在有效控制血糖的同时,能更好地摸拟生理性胰岛素分泌,有助于胰岛β细胞功能的恢复.
목적:탐구뢰포이도소50대초진2형당뇨병혈당화이도β세포공능적영향.방법:선취필자소재의원내분비과적주원초진위2형당뇨병환자공122례,채용전뇌적수궤적방법,장수시대상수궤분위상규조화뢰포조각61례,상규조용우비림혼합형、뢰포조용뢰포이도소50진행강당치료,측량량조환자치료전후각항혈당화C태상관지표적변화정황.결과:량조환자혈당도유량호적공제,상호몰유차이;단상규조환자치료전후C태수평몰유명현변화;뢰포조치료전후C태수평유명현변화,병차교상규조차이명현.결론:뢰포이도소50재유효공제혈당적동시,능경호지모의생이성이도소분비,유조우이도β세포공능적회복.
Objective:To explore the lispro impact of 50 newly diagnosed with type 2 diabetes and isletβ-cell function.The hospital diagnosed as type 2 diabetes patients with a total of 122 cases in our hospital Endocrinology,using computer random.Method:The subjects were randomly divided into conventional group and lispro group of 61 cases,the conventional group Humulin hybrid lispro group hypoglycemic treatment with lispro 50,measuring the blood glucose and C-peptide index changes in the two groups of patients before and after treatment.Have good.Result:Of two groups of patients with blood glucose control,with each other there is no difference;regular group of patients before and after treatment the C-peptide levels did not change significantly;significant change in C-peptide levels in the lispro group before and after treatment,and the differences are significant compared to the conventional group.Conclusion:Lispro 50 while in the effective control of blood glucose,better simulated physiological insulin secretion,contribute to the recovery ofβ-cell function.