中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
3期
485-486
,共2页
咪达唑仑%舒芬太尼%多发肋骨骨折%机械通气%镇痛镇静
咪達唑崙%舒芬太尼%多髮肋骨骨摺%機械通氣%鎮痛鎮靜
미체서륜%서분태니%다발륵골골절%궤계통기%진통진정
Midazolam%Sufentanil%Multiple Rib Fracture%Mechanical Ventilation%Sedation Analgesia
目的:探讨咪达唑仑-舒芬太尼在机械通气治疗多发肋骨骨折患者的中镇痛镇静效果.方法:18例接受机械通气患者均予首剂静脉注射咪达唑仑0.15~0.3mg/kg、舒芬太尼1~2μg/kg镇痛镇静负荷量,后予咪达唑仑0.05~0.1mg/kg/h、舒芬太尼0.3~1.5μg/kg/h微泵注射维持,根据患者情况个体化调整入量,维持镇静Ramsay评分在3~4分水平,通过监测患者心率、呼吸、平均动脉压及动脉血气分析进行治疗前后对比评估.结果:在负荷剂量及维持量下所有患者均能够达到目标镇痛镇静效果,Ramsay评分均在3~4分.患者用药1h后HR、RR、SaO2,平均动脉压及动脉血气pH值、PaO2、PaCO2均较用药前明显改善(P<0.01).结论:对ICU机械通气治疗多发性肋骨骨折的患者,咪达唑仑-舒芬太尼能显著提高患者的镇痛镇静效果,避免“人-机对抗”,改善氧合,降低耗氧,效果确切.
目的:探討咪達唑崙-舒芬太尼在機械通氣治療多髮肋骨骨摺患者的中鎮痛鎮靜效果.方法:18例接受機械通氣患者均予首劑靜脈註射咪達唑崙0.15~0.3mg/kg、舒芬太尼1~2μg/kg鎮痛鎮靜負荷量,後予咪達唑崙0.05~0.1mg/kg/h、舒芬太尼0.3~1.5μg/kg/h微泵註射維持,根據患者情況箇體化調整入量,維持鎮靜Ramsay評分在3~4分水平,通過鑑測患者心率、呼吸、平均動脈壓及動脈血氣分析進行治療前後對比評估.結果:在負荷劑量及維持量下所有患者均能夠達到目標鎮痛鎮靜效果,Ramsay評分均在3~4分.患者用藥1h後HR、RR、SaO2,平均動脈壓及動脈血氣pH值、PaO2、PaCO2均較用藥前明顯改善(P<0.01).結論:對ICU機械通氣治療多髮性肋骨骨摺的患者,咪達唑崙-舒芬太尼能顯著提高患者的鎮痛鎮靜效果,避免“人-機對抗”,改善氧閤,降低耗氧,效果確切.
목적:탐토미체서륜-서분태니재궤계통기치료다발륵골골절환자적중진통진정효과.방법:18례접수궤계통기환자균여수제정맥주사미체서륜0.15~0.3mg/kg、서분태니1~2μg/kg진통진정부하량,후여미체서륜0.05~0.1mg/kg/h、서분태니0.3~1.5μg/kg/h미빙주사유지,근거환자정황개체화조정입량,유지진정Ramsay평분재3~4분수평,통과감측환자심솔、호흡、평균동맥압급동맥혈기분석진행치료전후대비평고.결과:재부하제량급유지량하소유환자균능구체도목표진통진정효과,Ramsay평분균재3~4분.환자용약1h후HR、RR、SaO2,평균동맥압급동맥혈기pH치、PaO2、PaCO2균교용약전명현개선(P<0.01).결론:대ICU궤계통기치료다발성륵골골절적환자,미체서륜-서분태니능현저제고환자적진통진정효과,피면“인-궤대항”,개선양합,강저모양,효과학절.
@@@@Objective:To investigate the effects of midazolam-sufentanil during mechanical ventilation in the treatment of multiple ribs fracture patients in sedation and analgesia effect.Methods:18 cases of patients receiving mechanical ventilation to the first dose of intravenous midazolam 0.15~0.3mg/kg, with 1 to 2 μ g/kg of analgesic and sedation of load, then with midazolam 0.05~0.1mg/kg/h, with 0.3 to 1.5 μ g/kg/h micropump injection maintenance, according to patients condition a the amount of adjustment, maintain calm Ramsay score in the 3 to 4 level, heart rate, breathing through the monitoring of patients, mean arterial pressure and arterial blood gas analysis were compared before and after treatment to evaluate.Results: In the loading dose and maintenance dose of all patients were able to reach the goals of sedation and analgesia effect, Ramsay score was 3~4.Drug use in patients after 1h HR, RR, SaO2, mean arterial pressure and arterial blood gas pH, PaO2, PaCO2 were obviously improved than before treatment (P<0.01).Conclusion: ICU of mechanical ventilation in the treatment of multiple ribs fracture patients, midazolam - sufentanil can significantly improve patient sedation and analgesia effect, avoid“man machine confrontation”, improve oxygenation, reduce oxygen consumption, the exact effect.
