CAJ | 학술논문

目的:探讨小剂量聚乙二醇干扰素α-2a联合利巴韦林抗病毒治疗失代偿期丙型肝炎肝硬化的临床效果.方法:分析我院收治的失代偿丙型肝炎肝硬化患者临床资料,依据治疗方式不同进行分组,对照组(普通治疗组)30例和观察组(小剂量聚乙二醇干扰素α-2a联合利巴韦林抗病毒治疗组)30例.结果:观察组失代偿丙型肝炎肝硬化患者ALT、AST、ALB、TBIL、child pugh评分、HA、PCⅢ、LN均优于对照组,P<0.05,研究结果差异有统计学意义.结论:小剂量聚乙二醇干扰素α-2a联合利巴韦林抗病毒治疗失代偿丙型肝炎肝硬化临床症状改善明显,抗纤维化效果较好.
목적:탐토소제량취을이순간우소α-2a연합리파위림항병독치료실대상기병형간염간경화적림상효과.방법:분석아원수치적실대상병형간염간경화환자림상자료,의거치료방식불동진행분조,대조조(보통치료조)30례화관찰조(소제량취을이순간우소α-2a연합리파위림항병독치료조)30례.결과:관찰조실대상병형간염간경화환자ALT、AST、ALB、TBIL、child pugh평분、HA、PCⅢ、LN균우우대조조,P<0.05,연구결과차이유통계학의의.결론:소제량취을이순간우소α-2a연합리파위림항병독치료실대상병형간염간경화림상증상개선명현,항섬유화효과교호.
@@@@Objective:To approach clinical result of curing decompensated C hepatitis cirrhosis by small dose pegylated interferonα -2a and ribavirin. Method:To analyze clinical data of decompensated C hepatitis cirrhosis patients in our hospital,which was to be divided into,control group(ordinary treatment group)30 cases and detection group(small dose of pegylated interferonα-2a in combination with ribavirin antiviral therapy group)30 cases. Result:ALT,AST,ALB,TBIL,child pugh score,HA,PCⅢ,LN of detection group were better than control group,P<0.05,results the difference was statistically significant. Conclusion:The curing decompensated C hepatitis cirrhosis by small dose pegylated interferonα-2a and ribavirin were obviously,anti fibrosis effect is good.