CAJ | 학술논문

目的:比较丙泊酚复合瑞芬太尼与七氟醚复合笑气吸入两种麻醉药物使用方法对腹腔镜胆囊切除术应激反应的影响.方法:选取2011.1~2012.1在本院进行腹腔镜胆囊手术的50例病人.其中男31例,女29例,随即分为丙泊酚复合瑞芬太尼靶控输注静脉组(A组)和异氟醚复合笑气吸入麻醉组(B组),每组25例.比较术中患者各时点的MAP、HR、SpO2、PETCO2等相关指标变化情况和术后不良反应情况.结果:A组平均动脉压高于B组(P<0.05).两组患者心率均低于麻醉前数值,A组诱导后10min心率下降,低于吸入麻醉组(P<0.05).A组麻醉后不良反应发生率明显低于B组(P<0.05).结论:两种不同的麻醉药物组合方式均能维持腹腔镜胆囊手术中患者的血流动力学稳定,丙泊酚复合瑞芬太尼靶控麻醉效果更持久,不良反应更低.本研究为临床医生选择合适的麻醉方法提供了一定的参考依据.
목적:비교병박분복합서분태니여칠불미복합소기흡입량충마취약물사용방법대복강경담낭절제술응격반응적영향.방법:선취2011.1~2012.1재본원진행복강경담낭수술적50례병인.기중남31례,녀29례,수즉분위병박분복합서분태니파공수주정맥조(A조)화이불미복합소기흡입마취조(B조),매조25례.비교술중환자각시점적MAP、HR、SpO2、PETCO2등상관지표변화정황화술후불량반응정황.결과:A조평균동맥압고우B조(P<0.05).량조환자심솔균저우마취전수치,A조유도후10min심솔하강,저우흡입마취조(P<0.05).A조마취후불량반응발생솔명현저우B조(P<0.05).결론:량충불동적마취약물조합방식균능유지복강경담낭수술중환자적혈류동역학은정,병박분복합서분태니파공마취효과경지구,불량반응경저.본연구위림상의생선택합괄적마취방법제공료일정적삼고의거.
@@@@Objective:To evaluate the efficacy and side effect of target controlled infusion of sevoflurane and propofol on patients with laparoscopic cholecystectomy. Methods: 50 patients (ASAⅠ~Ⅱ) underwent laparoscopic cholecystectomy were randomized into propofol group(Group A, n=25) and sevoflurane group( Group B, n=20). The MAP, H R, SpO2 and PETCO2 were recorded before anesthesia induction and 5, 10, 15, 20min after tracheal intubation respectively. Recovery time and side effects were recorded during emergency period. Results:A group of mean arterial pressure than in group B (P<0.05). The two groups of patients with heart rate were lower than the pre-anesthetic value 10min after the A group induced heart rate decreased, lower than inhaled anesthesia group (P<0.05). The incidence of adverse reactions in the group A, anesthesia was significantly lower than that in group B (P<0.05). Conclusion:TCI propofol is easier to maintain stable hemodynamics than TCI sevoflurane, but the recovery time may be prolonged during emergency period. It must be selected reasonably according to the clinical situation.