中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
4期
676-677
,共2页
丁苯酞氯化钠注射液%内皮功能%脑梗死%观察
丁苯酞氯化鈉註射液%內皮功能%腦梗死%觀察
정분태록화납주사액%내피공능%뇌경사%관찰
Butylphthalide sodium chloride injection%Endothelial function%Cerebral infarction%Observed
目的:丁苯酞氯化钠注射液对脑梗死疗效及对内皮功能影响.方法:将急性脑梗死患者120例,随机分为治疗组和对照组各60例,两组患者均给予常规治疗,在此基础上治疗组给予丁苯钛氯化钠注射液100毫升,日一次静点,对照组用0.9%盐水+胞二磷胆碱1.0,日一次静点,治疗14天,两组常规抑制血小板、降颅压、控制血糖及调脂治疗.结果:观察组总有效率高于对照组,差异有统计学意义(P<0.05);两组患者治疗后14天的EF-Ⅰ,NO,TXA2,VEGF和CRP水平较入院次日明显得到改善,且治疗组患者治疗后14d的NO和EF-Ⅰ水平明显较对照组的高,而TXA2、VEGF和CRP的水平则明显低于对照组,两者比较差异均具有显著性(P均<0.05).结论:丁苯酞氯化钠注射液治疗脑梗死临床疗效显著,对内皮功能影响较小,值得借鉴.
目的:丁苯酞氯化鈉註射液對腦梗死療效及對內皮功能影響.方法:將急性腦梗死患者120例,隨機分為治療組和對照組各60例,兩組患者均給予常規治療,在此基礎上治療組給予丁苯鈦氯化鈉註射液100毫升,日一次靜點,對照組用0.9%鹽水+胞二燐膽堿1.0,日一次靜點,治療14天,兩組常規抑製血小闆、降顱壓、控製血糖及調脂治療.結果:觀察組總有效率高于對照組,差異有統計學意義(P<0.05);兩組患者治療後14天的EF-Ⅰ,NO,TXA2,VEGF和CRP水平較入院次日明顯得到改善,且治療組患者治療後14d的NO和EF-Ⅰ水平明顯較對照組的高,而TXA2、VEGF和CRP的水平則明顯低于對照組,兩者比較差異均具有顯著性(P均<0.05).結論:丁苯酞氯化鈉註射液治療腦梗死臨床療效顯著,對內皮功能影響較小,值得藉鑒.
목적:정분태록화납주사액대뇌경사료효급대내피공능영향.방법:장급성뇌경사환자120례,수궤분위치료조화대조조각60례,량조환자균급여상규치료,재차기출상치료조급여정분태록화납주사액100호승,일일차정점,대조조용0.9%염수+포이린담감1.0,일일차정점,치료14천,량조상규억제혈소판、강로압、공제혈당급조지치료.결과:관찰조총유효솔고우대조조,차이유통계학의의(P<0.05);량조환자치료후14천적EF-Ⅰ,NO,TXA2,VEGF화CRP수평교입원차일명현득도개선,차치료조환자치료후14d적NO화EF-Ⅰ수평명현교대조조적고,이TXA2、VEGF화CRP적수평칙명현저우대조조,량자비교차이균구유현저성(P균<0.05).결론:정분태록화납주사액치료뇌경사림상료효현저,대내피공능영향교소,치득차감.
@@@@Objective:To explore the combined with Austria grips Gray sodium in the treatment of cerebral infarction. Methods:120 cases of acute cerebral infarction patients, were randomly divided into observation group and control group. The observation group of 60 cases, 60 cases of the control group. Two groups were given conventional treatment, on the basis of the observation group received Shuxuening Injection 20ml, adding 250ml saline infusion, 1 times/d. While giving the Austria grips Gray sodium 80mg in 100ml saline infusion, 2/D, 14d total of application. The control group on the basis of routine treatment given to Austria grips Gray sodium 80mg in 250ml saline infusion, 2/D, 14d total of application. Results:In the study group, the total efficiency of the control group, the difference was statistically significant (P>0.05). After 14 days of the treatment,these two groups’ patients’ EF-Ⅰ, NO, TXA2, VEGF and CRP level have improved significantly, what’s more, treatment group’s patients’ NO and EF-Ⅰlevel are obviously higher than control group’s,while TXA2、VEGF and CRP level are obviously lower than control group's after 14 days of the treatment,both comparative differences are significant(P<0.05). Conclusion:Combined with Austria grips Gray sodium in the treatment of cerebral infarction clinical curative effect, is worth to draw lessons from.
