CAJ | 학술논문

糖尿病动物模型在糖尿病以及其并发症发病机制的研究中应用极其广泛,并且已有较长历史.除此之外,所有针对糖尿病治疗的措施,包括胰腺细胞的移植,甚至是预防策略,都要预先在动物模型上开展并观察.因此,对糖尿病动物模型进行研究和优化,使其更接近人类糖尿病发病过程,将有助于深入研究糖尿病及其并发症的发病机制,并为治疗和预防糖尿病奠定重要基础.
당뇨병동물모형재당뇨병이급기병발증발병궤제적연구중응용겁기엄범,병차이유교장역사.제차지외,소유침대당뇨병치료적조시,포괄이선세포적이식,심지시예방책략,도요예선재동물모형상개전병관찰.인차,대당뇨병동물모형진행연구화우화,사기경접근인류당뇨병발병과정,장유조우심입연구당뇨병급기병발증적발병궤제,병위치료화예방당뇨병전정중요기출.
Animal models have been used extensively in diabetes research for a long time. Apart from their use in studying the pathogenesis of the disease and its complications,all new treatments for diabetes,including islet cell transplantation and preventative strategies,are initially investigated in animals. Therefore,improving experimental diabetic animal models and looking for excellent models of human-like pathogenic process of diabetes become much more significant in the pathogenesis of diabetes and its complications.