CAJ | 학술논문

目的探讨奥曲肽、垂体后叶素治疗肝硬化上消化道出血的疗效.方法将肝硬化上消化道出血的120例患者,随机分为奥曲肽组和垂体后叶素组,观察2组患者止血和不良反应发生情况.结果奥曲肽组治疗的临床显效率、总有效率明显高于例垂体后叶素组[40.0%(24/60)比21.7%(13/60),75.0%(45/60)比53.3%(32/60)](P<0.05),奥曲肽组止血时间、不良反应发生率均明显低于垂体后叶素组[(21±11)h比(34±14)h,8.3%(5/60)比38.3%(23/60)](P<0.01).结论在肝硬化上消化道出血的治疗中,奥曲肽的疗效高于垂体后叶素,具有一定临床价值.
목적탐토오곡태、수체후협소치료간경화상소화도출혈적료효.방법장간경화상소화도출혈적120례환자,수궤분위오곡태조화수체후협소조,관찰2조환자지혈화불량반응발생정황.결과오곡태조치료적림상현효솔、총유효솔명현고우례수체후협소조[40.0%(24/60)비21.7%(13/60),75.0%(45/60)비53.3%(32/60)](P<0.05),오곡태조지혈시간、불량반응발생솔균명현저우수체후협소조[(21±11)h비(34±14)h,8.3%(5/60)비38.3%(23/60)](P<0.01).결론재간경화상소화도출혈적치료중,오곡태적료효고우수체후협소,구유일정림상개치.
Objective To investigate the efficacy of octreotide, pituitrin in treatment of upper gastrointestinal hemorrhage in hepatic cirrhosis. Methods Chose 120 patients with upper upper gastrointestinal hemorrhage in hepatic cirrhosis, and divided them into two groups, the octreotide group and pituitrin group. The hemostasis and adverse reactions were observed in two groups. Results Clinically significant efficiency, total efficiency of the octreotide group was significantly higher than the pituitrin group (P<0.05), hemostatic time and adverse reaction rates of the octreotide group were significantly lower than the pituitrin group (P<0.01). Conclusion In the treatment of upper gastrointestinal hemorrhage in hepatic cirrhosis, the efficacy of the octreotide group is higher than the pituitary group, it has a certain clinical value.