当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2013年
2期
5-6
,共2页
杜自忠%杨维建%张明星%黄邦荣
杜自忠%楊維建%張明星%黃邦榮
두자충%양유건%장명성%황방영
脾动脉栓塞%门静脉高压%思他宁%介入治疗
脾動脈栓塞%門靜脈高壓%思他寧%介入治療
비동맥전새%문정맥고압%사타저%개입치료
Splenic artery embolization%Portal hypertension%Somatostatin%Intervention therapy
目的探讨部分脾动脉栓塞联合思他宁灌注治疗门静脉高压、脾功能亢进的临床效果.方法60例肝硬化门静脉高压症合并脾功能亢进病人,在一次性操作中先用思他宁灌注,然后进行部分脾动脉栓塞.随访手术前后门静脉压力参数改变、脾功能变化、食管胃底曲张静脉程度改变.结果60例病人手术操作均成功,门静脉压力从(32.8±2.87)mmHg降到(15.10±1.14)mmHg,门静脉内径从(1.46±0.43)cm回缩到(1.27±0.43)cm,门脉血流量从(1538.51±4.48)mL/min减少到(1208.11±9.28)mL/min,术前术后比较三者差异均有统计学意义,58例术后内窥镜及食道钡餐检查曲张静脉好转.结论脾动脉栓塞联合思他宁灌注治疗门静脉高压、脾功能亢进,可明显降低门静脉压力,改善脾功能亢进,是一种安全、有效的介入治疗方法.
目的探討部分脾動脈栓塞聯閤思他寧灌註治療門靜脈高壓、脾功能亢進的臨床效果.方法60例肝硬化門靜脈高壓癥閤併脾功能亢進病人,在一次性操作中先用思他寧灌註,然後進行部分脾動脈栓塞.隨訪手術前後門靜脈壓力參數改變、脾功能變化、食管胃底麯張靜脈程度改變.結果60例病人手術操作均成功,門靜脈壓力從(32.8±2.87)mmHg降到(15.10±1.14)mmHg,門靜脈內徑從(1.46±0.43)cm迴縮到(1.27±0.43)cm,門脈血流量從(1538.51±4.48)mL/min減少到(1208.11±9.28)mL/min,術前術後比較三者差異均有統計學意義,58例術後內窺鏡及食道鋇餐檢查麯張靜脈好轉.結論脾動脈栓塞聯閤思他寧灌註治療門靜脈高壓、脾功能亢進,可明顯降低門靜脈壓力,改善脾功能亢進,是一種安全、有效的介入治療方法.
목적탐토부분비동맥전새연합사타저관주치료문정맥고압、비공능항진적림상효과.방법60례간경화문정맥고압증합병비공능항진병인,재일차성조작중선용사타저관주,연후진행부분비동맥전새.수방수술전후문정맥압력삼수개변、비공능변화、식관위저곡장정맥정도개변.결과60례병인수술조작균성공,문정맥압력종(32.8±2.87)mmHg강도(15.10±1.14)mmHg,문정맥내경종(1.46±0.43)cm회축도(1.27±0.43)cm,문맥혈류량종(1538.51±4.48)mL/min감소도(1208.11±9.28)mL/min,술전술후비교삼자차이균유통계학의의,58례술후내규경급식도패찬검사곡장정맥호전.결론비동맥전새연합사타저관주치료문정맥고압、비공능항진,가명현강저문정맥압력,개선비공능항진,시일충안전、유효적개입치료방법.
Objective To explore the therapeutic effect of artery embolization combined somatostatin perfusion to cure portal hypertension, spleen hyperfunction. Methods 60 cases of liver cirrhosis portal hypertension and spleen hyperfunction patients, in the intervention operation ,first of infusion somatostatin, then part of the splenic artery were embolized after measurement portal vein pressure before and after operation, spleen volume, stomach esophagus vein of change. Results 60 patients operation success,the portal vein pressure from (32.8 ±2.87) mmHg to (15.10 ±1.14) mmHg, portal vein inner diameter from (1.46 ±0.43) cm retraction to (1.27 ±0.43) cm, portal blood flow from (1538.51 ±4.48)mL/min reduced to (1208.11 ±9.28) mL/min, preoperative after it was statistically significant difference of three, 58 cases of esophageal varicose vein postoperative endoscope resuit was better than preopration. Conclusion Splenic artery embolization combined somatostatin reperfusion cureed portal vain hypertension, spleen hyperfunction, can obviously reduce portal vein pressure , improve the function of spleen, is a safe and effective intervention therapy of curing liver cirrhosis, portal hypertension ,stomach esophagus rupture and spleen hyperfunction.