CAJ | 학술논문

分化型甲状腺癌包括乳头状癌和滤泡性癌,其治疗以外科手术为主.关于分化型甲状腺癌原发病灶手术切除的合适范围、颈淋巴结清扫的适应证和范围、术后甲状腺残余放射性碘去除的作用和甲状腺素抑制治疗等方面,目前仍存争议.本文从循证医学的角度去探索和解释分化型甲状腺癌外科治疗问题,并综述相关研究进展.结果表明对于分化型甲状腺癌,适当与精确的检查治疗手段与选择合理的手术方式十分重要,可有效减少术后癌症复发和再次手术的几率.
분화형갑상선암포괄유두상암화려포성암,기치료이외과수술위주.관우분화형갑상선암원발병조수술절제적합괄범위、경림파결청소적괄응증화범위、술후갑상선잔여방사성전거제적작용화갑상선소억제치료등방면,목전잉존쟁의.본문종순증의학적각도거탐색화해석분화형갑상선암외과치료문제,병종술상관연구진전.결과표명대우분화형갑상선암,괄당여정학적검사치료수단여선택합리적수술방식십분중요,가유효감소술후암증복발화재차수술적궤솔.
Diferentiated thyroid cancer(DTC)presents as a solitary thyroid nodule,as multinodular goiter, or as a neck mass.Surgery is the treatment of choice and most of the specialists consider that total thyroidectomy with central cervical lymph nodes dissection must be applied in all patients.Some specialists prefer a more conservative surgical treatment in order to avoid complications.Papillary and follicular thyroid carcinomas are the most common thyroid malignancies and are usually indolent.Lymph-node involvement increases the rate of tumor recurrence and reduces long-term survival.We concluded that DTC has an aggressive behavior at presentation.Recent advances in the understanding of DTC tumor biology hold promise for improving the ability to predict tumor behavior and surgery model,thereby allowing more appropriate risk stratification,imaging surveillance, and treatment.