当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2013年
7期
95
,共1页
血清总胆汁酸%早产儿%胃肠外营养相关性胆汁淤积%诊断
血清總膽汁痠%早產兒%胃腸外營養相關性膽汁淤積%診斷
혈청총담즙산%조산인%위장외영양상관성담즙어적%진단
Serum total bile acid%Premature%Parenteral nutrition associated cholestasis%Diagnosis
目的探讨血清总胆汁酸对早产儿胃肠外营养相关性胆汁淤积的诊断意义.方法选取2010年1月~2012年3月广东省信宜市人民医院收治的早产儿118例,分为实验组(有胃肠外营养相关性胆汁淤积)和对照组(无胃肠外营养相关性胆汁淤积),记录全部早产儿的血清总胆汁酸(TBA)、谷氨酰转肽酶(GGT)及碱性磷酸酶(ALP).结果 TBA的灵敏度和特异度均高于GGT、ALP指标,当血清TBA≥25.8μmol/L时,其灵敏度、特异度分别为88.3%和88.1%.结论血清TBA检测更利于胃肠外营养相关性胆汁淤积的早期诊断,具有重要的临床意义.
目的探討血清總膽汁痠對早產兒胃腸外營養相關性膽汁淤積的診斷意義.方法選取2010年1月~2012年3月廣東省信宜市人民醫院收治的早產兒118例,分為實驗組(有胃腸外營養相關性膽汁淤積)和對照組(無胃腸外營養相關性膽汁淤積),記錄全部早產兒的血清總膽汁痠(TBA)、穀氨酰轉肽酶(GGT)及堿性燐痠酶(ALP).結果 TBA的靈敏度和特異度均高于GGT、ALP指標,噹血清TBA≥25.8μmol/L時,其靈敏度、特異度分彆為88.3%和88.1%.結論血清TBA檢測更利于胃腸外營養相關性膽汁淤積的早期診斷,具有重要的臨床意義.
목적탐토혈청총담즙산대조산인위장외영양상관성담즙어적적진단의의.방법선취2010년1월~2012년3월광동성신의시인민의원수치적조산인118례,분위실험조(유위장외영양상관성담즙어적)화대조조(무위장외영양상관성담즙어적),기록전부조산인적혈청총담즙산(TBA)、곡안선전태매(GGT)급감성린산매(ALP).결과 TBA적령민도화특이도균고우GGT、ALP지표,당혈청TBA≥25.8μmol/L시,기령민도、특이도분별위88.3%화88.1%.결론혈청TBA검측경리우위장외영양상관성담즙어적적조기진단,구유중요적림상의의.
Objective To investigate the diagnosis of Serum total bile acid on parenteral nutrition associated cholestasis for premature. Methods There were 118 premature in our hospital from Jan 2010 to Mar 2012 divided into the experiment group,which with parenteral nutrition associated cholestasis, and the control group, which without parenteral nutrition associated cholestasis. The experiment group used EMIC while the control group used three-hole method. Results The sensitivity and specificity of TBA were higher than GGT and ALP. The sensitivity and specificity of TBA were 88.3%and 88.1%when Serum total bile acid more than 25.8μmol/L. Conclusion The serum total bile acid has an important clinic meaning, for whose detection is beneficial to early diagnosis for parenteral nutrition associated cholestasis.
