CAJ | 학술논문

目的探讨慢性阻塞性肺疾病(Chronic obstructive pulmonary disease,COPD)患者抗菌药物的使用现状,以供临床参考.方法选取2009年8月~2012年7月中山市沙溪隆都医院收治的COPD患者175例为研究对象,回顾性分析其临床资料,探讨COPD患者抗菌药物使用种类、使用时间、使用频率、药物利用指数(DUI)、联合用药等方面的合理性.结果所有患者均使用抗菌药物治疗,使用率100%.品种包括7类18种,使用频率前3位的有左氧氟沙星、阿奇霉素和阿莫西林.使用时间3~10 d,平均用药时间(6.12±2.05)d;其中单一用药83例、二联用药68例、三联用药24例.应用最多的3种药物的DUI为阿奇霉素>左氧氟沙星>阿莫西林.结论在COPD的临床治疗中,抗菌药物的使用存在一定的不合理之处,今后在临床用药时,应予以纠正.
목적탐토만성조새성폐질병(Chronic obstructive pulmonary disease,COPD)환자항균약물적사용현상,이공림상삼고.방법선취2009년8월~2012년7월중산시사계륭도의원수치적COPD환자175례위연구대상,회고성분석기림상자료,탐토COPD환자항균약물사용충류、사용시간、사용빈솔、약물이용지수(DUI)、연합용약등방면적합이성.결과소유환자균사용항균약물치료,사용솔100%.품충포괄7류18충,사용빈솔전3위적유좌양불사성、아기매소화아막서림.사용시간3~10 d,평균용약시간(6.12±2.05)d;기중단일용약83례、이련용약68례、삼련용약24례.응용최다적3충약물적DUI위아기매소>좌양불사성>아막서림.결론재COPD적림상치료중,항균약물적사용존재일정적불합리지처,금후재림상용약시,응여이규정.
Objective Analyse antibacterial drug use situation of chronic obstructive pulmonary disease, for clinical reference. Methods Choose 175 cases from Aug. 2009 to Jul. 2012 in our hospital as study object, a retrospective analysis of clinical data, chronic obstructive pulmonary disease patients antibiotic use, frequency of use, types of use time, drug utilization index ( DUI ), in conjunction with the rationality of medicine etc. Results All patients use antibacterial drugs, use rate of 100%. Species include 7 categories 18 kinds, the top 3 were levofloxacin, azithromycin and amoxicillin. The use time was 3~10 d, average time was ( 6.12 ±2.05) d;single drug in 83 cases, two drugs in 68 cases, triple therapy in 24 cases. The three drug DUI azithromycin>levofloxacin>amoxicillin. Conclusion In treatment of chronic obstructive pulmonary disease, the use of antibacterial drugs exist some unreasonable, in future clinical medication should be corrected.