CAJ | 학술논문

牙髓病和根尖周病是以厌氧菌感染为主的混合感染性疾病,根管持续的感染状态是根管治疗失败的最重要原因之一.近年关于感染根管的细菌群落组成及菌群中细菌之间关系的研究较多,而且应用了克隆文库、核酸杂交、16S rDNA 指纹技术等多种分子生物学方法.本文将对近年来感染根管的分子生物学检测研究进展作一综述.
아수병화근첨주병시이염양균감염위주적혼합감염성질병,근관지속적감염상태시근관치료실패적최중요원인지일.근년관우감염근관적세균군락조성급균군중세균지간관계적연구교다,이차응용료극륭문고、핵산잡교、16S rDNA 지문기술등다충분자생물학방법.본문장대근년래감염근관적분자생물학검측연구진전작일종술.
Pulpitis and apical periodontitis are mainly of mixed infection of anaerobic bacteria infection, one of the most important reason of clinical failed root canal therapy is the continuous infected state of root canal. Clone library, nucleic acid hybridization, 16S rDNA fingerprint and other molecular biological techniques are commonly used to detect the bacteria composition and function. This review presents the molecular methods applied in infec-tious root canal.