CAJ | 학술논문

口腔癌是严重危害人类健康的疾病之一,患者在疾病的早期对其认识不足,往往使其得不到有效的控制;加之咀嚼和言语等活动的刺激,常使其在早期便发生转移,从而导致患者预后较差.研究显示,涎液中存在的一些分子物质与口腔癌的发生发展之间存在着一定的相关性,这就为其早期诊断和治疗以及改善患者预后提供了可能.本文就涎液成分的检测和口腔癌分子标志物的筛选等研究进展作一综述.
구강암시엄중위해인류건강적질병지일,환자재질병적조기대기인식불족,왕왕사기득불도유효적공제;가지저작화언어등활동적자격,상사기재조기편발생전이,종이도치환자예후교차.연구현시,연액중존재적일사분자물질여구강암적발생발전지간존재착일정적상관성,저취위기조기진단화치료이급개선환자예후제공료가능.본문취연액성분적검측화구강암분자표지물적사선등연구진전작일종술.
Oral cancer is a one of the most important killer which threaten human’s healthy severely. People usually have little acquaintance with it and treat it not seriously enough at the early stage; Additionally, the sti-mulations from the movement of the tongue and oral cavity when people are masticating and talking also can pro-mote cancer cells metastasis. Consequently, the prognosis of oral cancer is usually pessimistic. In the recent years, some research validated that some molecules correlate with the tumorigenesis and progression of oral cancer, which provide probability for the early diagnosis and therapy for the oral cancer. Therefore, this review will discuss the detection of saliva and the selection of the biomarkers of the oral cancer.