CAJ | 학술논문

[目的]观察低分子肝素治疗高原红细胞增多症(HAPC)的临床疗效.[方法]将60例 HAPC 患者随机分为治疗组与对照组各30例 . 对照组给予常规治疗(呼吸功能锻炼、间歇吸氧流量1~2 L /min ,每次1~2 h ,2~3次/日、红景天600 mg ,2次/日,15 d 一疗程).治疗组在常规治疗的基础上加用低分子肝素5000 IU 腹壁皮下注射,12 h 1次,10~14 d 为1疗程,比较两组疗效.[结果]治疗组:显效22例,有效7例,无效 l 例,总有效率96.7%;对照组:显效10例,有效 5 例,无效15 例,总有效率50%.治疗组总有效率明显高于对照组,且两组相比较差异有显著性( P <0.05).[结论]低分子肝素治疗 HAPC 安全有效.
[목적]관찰저분자간소치료고원홍세포증다증(HAPC)적림상료효.[방법]장60례 HAPC 환자수궤분위치료조여대조조각30례 . 대조조급여상규치료(호흡공능단련、간헐흡양류량1~2 L /min ,매차1~2 h ,2~3차/일、홍경천600 mg ,2차/일,15 d 일료정).치료조재상규치료적기출상가용저분자간소5000 IU 복벽피하주사,12 h 1차,10~14 d 위1료정,비교량조료효.[결과]치료조:현효22례,유효7례,무효 l 례,총유효솔96.7%;대조조:현효10례,유효 5 례,무효15 례,총유효솔50%.치료조총유효솔명현고우대조조,차량조상비교차이유현저성( P <0.05).[결론]저분자간소치료 HAPC 안전유효.
Objective] To observe the clinical efficacy of low molecular heparin for the treatment of patients with high altitude polycythemia(HAPC) .[Methods] A total of 60 HAPC patients were randomly divided into treatment group (n = 30) and control group( n = 30) .The control group was given routine treatment (respiratory function exercise ,inter‐mittent oxygen flow with 1 ~ 2 L/min once per 1 ~ 2 h and twice or three time a day ,and Hongjingtian 600mg twice a day for a course of 15d) .The treatment group was treated with routine therapy plus abdominal subcutaneous injection of low molecular weight heparin 5000 IU once per 12h for a course of 10 ~ 14d .The efficacy was compared between 2 groups .[Results]In the treatment group ,22 patients were excellent ,and 7 patients were effective ,and 1 patient was ineffective , and the total effective rate was 96 .7% .In the control group ,10 patients were excellent ,and 5 patients were effective , and 15 patients were ineffective ,and the total effective rate was 50% .The total effective rate in treatment group was ob‐viously higher than that in control group ,and there was significant difference between 2 groups( P < 0 .05) .[Conclu‐sion] Low molecular heparin for the treatment of HAPC is safe and effective .