CAJ | 학술논문

[目的]观察静脉注射硫酸镁对瑞芬太尼致妇科腔镜手术患者术后痛觉过敏的影响.[方法]择期行妇科腔镜手术患者56例,ASA Ⅰ~Ⅱ级,随机分为 A 组和 B 组,每组28例. B 组诱导前5 min 静脉注射硫酸镁40 mg/kg ,并以10 mg/(kg ? h)的速度输注至手术结束,A 组输入等剂量生理盐水.维持麻醉:瑞芬太尼0.4μg/(kg ? min),丙泊酚4 mg/(kg ? h).记录术后30 min 、1 h 、4 h 、12 h 、24 h VAS 评分,24 h 内追加芬太尼的量及不良反应的情况.[结果]A 组患者术后30 min 至4 h 之间的 VAS 评分明显高于 B 组( P <0.05);A 组停瑞芬太尼后第一次应用芬太尼的时间比 B 组明显提前( P < 0.05),且术后24 h 应用芬太尼的总量也明显较多( P < 0.05). A 组术后不良反应的发生率也高于 B 组( P < 0.05). [结论]硫酸镁可以缓解瑞芬太尼致妇科腔镜手术患者术后痛觉过敏.
[목적]관찰정맥주사류산미대서분태니치부과강경수술환자술후통각과민적영향.[방법]택기행부과강경수술환자56례,ASA Ⅰ~Ⅱ급,수궤분위 A 조화 B 조,매조28례. B 조유도전5 min 정맥주사류산미40 mg/kg ,병이10 mg/(kg ? h)적속도수주지수술결속,A 조수입등제량생리염수.유지마취:서분태니0.4μg/(kg ? min),병박분4 mg/(kg ? h).기록술후30 min 、1 h 、4 h 、12 h 、24 h VAS 평분,24 h 내추가분태니적량급불량반응적정황.[결과]A 조환자술후30 min 지4 h 지간적 VAS 평분명현고우 B 조( P <0.05);A 조정서분태니후제일차응용분태니적시간비 B 조명현제전( P < 0.05),차술후24 h 응용분태니적총량야명현교다( P < 0.05). A 조술후불량반응적발생솔야고우 B 조( P < 0.05). [결론]류산미가이완해서분태니치부과강경수술환자술후통각과민.
Objective] To observe the effect of intravenous magnesium sulfate on postoperative hyperalgesia caused by remifentanil in patients undergoing gynecologic laparoscopic surgery .[Methods] Totally 56 ASA Ⅰ ~ Ⅱ pa‐tients undergoing elective gynecological laparoscopic surgery were randomly divided into group A and group B with 28 cases in each group .Group B was infused with 40mg/kg magnesium sulfate intravenously 5min before the induction and then continuously infused by the velocity of 10mg/kg/h until the end of surgery .Group A was infused with equal dose of normal saline .Remifentanil 0 .4μg/kg/min and propofol 4mg/kg/h were used to maintain anesthesia .VAS score at 30min ,1h ,4h ,12h and 24h after operation ,the additional amount of fentanyl within 24h and adverse reac‐tions were recorded .[Results] VAS score from 30min to 4h in group A after operation was significantly higher than that in group B( P < 0 .05) .The first time of fentanyl used in group A after stopping remifentanil was significantly earlier than that in group B( P < 0 .05) ,and the total amount of fentanyl 24h after operation obviously increased( P< 0 .05) .The incidence of postoperative adverse reactions in group A was also higher that in group B ( P < 0 .05) .[Conclusion] Magnesium sulfate can alleviate postoperative hyperalgesia induced by remifentanil in patients undergo ‐ing gynecologic laparoscopic surgery .