医学临床研究
醫學臨床研究
의학림상연구
JOURNAL OF CLINICAL RESEARCH
2012年
10期
1930-1932
,共3页
冠状动脉疾病%臂%踝
冠狀動脈疾病%臂%踝
관상동맥질병%비%과
Coronary disease%arm%ankle
[目的]探讨静息和运动后的踝臂指数(ankle brachial index ,ABI)与冠状动脉狭窄程度的关系.[方法]选取在邵阳市中心医院心血管内科住院行冠状动脉造影患者120例,根据造影结果分为冠脉正常组( n =22)、轻‐中度病变组( n =54)和严重病变组( n =44),检测三组患者的血脂、血糖指标,比较三组的静息ABI 、运动后 ABI 、Gensini 积分,并对静息 ABI 、运动后 ABI 与冠状动脉狭窄程度进行相关性分析.[结果]严重病变组的静息 ABI 、运动后 ABI 水平明显低于与正常组、轻中度病变组(均 P <0.05);随病变程度增加Gensini 积分显著增加( P 均 <0.01 );静息 ABI 与运动后 ABI 与冠状动脉狭窄程度评分呈负相关(r =-0.55、-0.89,P <0.01). ROC 分析显示运动 ABI 的 ROC 图曲线下面积(0.752)大于静息 ABI 的 ROC图曲线下面积(0.646),但无统计学差异( P > 0.05). [结论]静息 ABI 及运动后 ABI 水平与冠脉狭窄程度相关,以运动后 ABI 相关性更密切,运动后 ABI 对严重冠状动脉狭窄程度具有更高的诊断价值.
[目的]探討靜息和運動後的踝臂指數(ankle brachial index ,ABI)與冠狀動脈狹窄程度的關繫.[方法]選取在邵暘市中心醫院心血管內科住院行冠狀動脈造影患者120例,根據造影結果分為冠脈正常組( n =22)、輕‐中度病變組( n =54)和嚴重病變組( n =44),檢測三組患者的血脂、血糖指標,比較三組的靜息ABI 、運動後 ABI 、Gensini 積分,併對靜息 ABI 、運動後 ABI 與冠狀動脈狹窄程度進行相關性分析.[結果]嚴重病變組的靜息 ABI 、運動後 ABI 水平明顯低于與正常組、輕中度病變組(均 P <0.05);隨病變程度增加Gensini 積分顯著增加( P 均 <0.01 );靜息 ABI 與運動後 ABI 與冠狀動脈狹窄程度評分呈負相關(r =-0.55、-0.89,P <0.01). ROC 分析顯示運動 ABI 的 ROC 圖麯線下麵積(0.752)大于靜息 ABI 的 ROC圖麯線下麵積(0.646),但無統計學差異( P > 0.05). [結論]靜息 ABI 及運動後 ABI 水平與冠脈狹窄程度相關,以運動後 ABI 相關性更密切,運動後 ABI 對嚴重冠狀動脈狹窄程度具有更高的診斷價值.
[목적]탐토정식화운동후적과비지수(ankle brachial index ,ABI)여관상동맥협착정도적관계.[방법]선취재소양시중심의원심혈관내과주원행관상동맥조영환자120례,근거조영결과분위관맥정상조( n =22)、경‐중도병변조( n =54)화엄중병변조( n =44),검측삼조환자적혈지、혈당지표,비교삼조적정식ABI 、운동후 ABI 、Gensini 적분,병대정식 ABI 、운동후 ABI 여관상동맥협착정도진행상관성분석.[결과]엄중병변조적정식 ABI 、운동후 ABI 수평명현저우여정상조、경중도병변조(균 P <0.05);수병변정도증가Gensini 적분현저증가( P 균 <0.01 );정식 ABI 여운동후 ABI 여관상동맥협착정도평분정부상관(r =-0.55、-0.89,P <0.01). ROC 분석현시운동 ABI 적 ROC 도곡선하면적(0.752)대우정식 ABI 적 ROC도곡선하면적(0.646),단무통계학차이( P > 0.05). [결론]정식 ABI 급운동후 ABI 수평여관맥협착정도상관,이운동후 ABI 상관성경밀절,운동후 ABI 대엄중관상동맥협착정도구유경고적진단개치.
Objective] To explore the relationship between ankle‐brachial index(ABI) at rest and after ex‐ercise and coronary artery stenosis .[Methods] Totally 120 patients receiving coronary angiography in central hospital of Shaoyang city were selected .According to coronary angiography ,all patients were divided into nor‐mal coronary artery group( n = 22) ,mild‐moderate lesion group( n = 54) and severe lesion group( n = 44) . Resting and postexercise ABI and Gensini score were compared among 3 groups .The correlation of resting and postexercise ABI with coronary artery stenosis was analyzed .[Results] Resting and postexercise ABI in severe lesion group was obviously lower than that in normal group and mild‐moderate lesion group ( P < 0 .05) . Gensini scores increased significantly with the increasing of lesion severity ( P < 0 .01) .Resting and postexer‐cise ABI was negatively related to coronary stenosis scores (r = - 0 .55 , - 0 .89 ,P < 0 .01) .ROC analysis showed that the area under the curve of ROC of exercise ABI (0 .752) was larger than that of resting ABI (0 .646) ,but there was no significant difference .[Conclusion] Resting and postexercise ABI is related to coro‐nary stenosis ,and the correlation of postexercise ABI with coronary stenosis is closer .Postexercise ABI has higher value for the diagnosis of sever coronary artery stenosis .
