医学临床研究
醫學臨床研究
의학림상연구
JOURNAL OF CLINICAL RESEARCH
2012年
10期
1940-1942
,共3页
马丽霞%傅广*%汤华%石顺华%黄树斌
馬麗霞%傅廣*%湯華%石順華%黃樹斌
마려하%부엄*%탕화%석순화%황수빈
冠状动脉疾病%绝经
冠狀動脈疾病%絕經
관상동맥질병%절경
Coronary disease%menopause
[目的]分析未绝经女性冠心病患者的临床特点.[方法]对136例女性冠心病患者分为未绝经女性冠心病组(29例)与已绝经女性冠心病组(107例),分析两组患者的冠心病危险因素、临床发病及冠脉造影特点.[结果]未绝经冠心病组高血压、糖尿病、高脂血症的发生率及冠心病传统危险因素个数均显著低于已绝经冠心病组( P <0.05);未绝经冠心病组6.9%的患者只合并抑郁;未绝经冠心病组以急性冠脉综合征(ACS)起病比例显著高于已绝经冠心病组(72.4%比30.8%,P <0.01);未绝经冠心病组单支病变比例高于已绝经冠心病组(65.5%比28.0%,P <0.05),且以前降支更容易受累.[结论]未绝经冠心病组冠心病传统危险因素少于已绝经冠心病组,抑郁情绪可能与冠心病的发病有关,多以 ACS 起病,临床工作中,应注意避免未绝经女性冠心病患者的漏诊.
[目的]分析未絕經女性冠心病患者的臨床特點.[方法]對136例女性冠心病患者分為未絕經女性冠心病組(29例)與已絕經女性冠心病組(107例),分析兩組患者的冠心病危險因素、臨床髮病及冠脈造影特點.[結果]未絕經冠心病組高血壓、糖尿病、高脂血癥的髮生率及冠心病傳統危險因素箇數均顯著低于已絕經冠心病組( P <0.05);未絕經冠心病組6.9%的患者隻閤併抑鬱;未絕經冠心病組以急性冠脈綜閤徵(ACS)起病比例顯著高于已絕經冠心病組(72.4%比30.8%,P <0.01);未絕經冠心病組單支病變比例高于已絕經冠心病組(65.5%比28.0%,P <0.05),且以前降支更容易受纍.[結論]未絕經冠心病組冠心病傳統危險因素少于已絕經冠心病組,抑鬱情緒可能與冠心病的髮病有關,多以 ACS 起病,臨床工作中,應註意避免未絕經女性冠心病患者的漏診.
[목적]분석미절경녀성관심병환자적림상특점.[방법]대136례녀성관심병환자분위미절경녀성관심병조(29례)여이절경녀성관심병조(107례),분석량조환자적관심병위험인소、림상발병급관맥조영특점.[결과]미절경관심병조고혈압、당뇨병、고지혈증적발생솔급관심병전통위험인소개수균현저저우이절경관심병조( P <0.05);미절경관심병조6.9%적환자지합병억욱;미절경관심병조이급성관맥종합정(ACS)기병비례현저고우이절경관심병조(72.4%비30.8%,P <0.01);미절경관심병조단지병변비례고우이절경관심병조(65.5%비28.0%,P <0.05),차이전강지경용역수루.[결론]미절경관심병조관심병전통위험인소소우이절경관심병조,억욱정서가능여관심병적발병유관,다이 ACS 기병,림상공작중,응주의피면미절경녀성관심병환자적루진.
Objective] To analyze clinical characteristics of premenopausal women with coronary heart dis‐ease(CHD) .[Methods] A total of 136 female patients with CHD were divided into female premenopausal CHD group( n = 29) and female menopausal CHD group( n = 107) .The risk factor of coronary heart disease , clinical pathogenesis and coronary angiographic characteristics in 2 groups were analyzed .[Results] The inci‐dence of hypertension ,diabetes mellitus and hyperlipidemia and the common risk factors of CHD in premeno ‐pausal CAD group were significantly lower than those in menopausal CHD group ( P < 0 .05) .Depression was observed in 6 .9% of premenopausal CHD patients .The proportion of acute coronary syndrome(ACS) in pre‐menopausal CHD group was significantly higher than that in menopausal CHD group (72 .4% vs 30 .8% ,P <0 .01) .The proportion of single vessel lesion in premenopausal CHD group was higher than that in menopausal CHD group(65 .5% vs 28 .0% ,P < 0 .05) ,and anterior descending branch was easy to be involved in .[Con‐clusion] The common risk factors of premenopausal CHD group are less than those in menopausal CHD group . Depression mood may be related with the pathogenesis of CHD ,and the main onset is ASC .The missed diag‐nosis of premenopausal CHD patients should be avoided in clinical practice .